Results 171 to 180 of about 1,574,651 (334)

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

FEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi, Xin Gao, Takashi Gojobori   +2 more
wiley   +1 more source

GENE-ENVIRONMENT INTERACTION AS A HEAD AND NECK CANCER RESEARCH STRATEGY

, 2000

openalex   +1 more source

Gene–environment interaction modulated by allelic heterogeneity in inflammatory diseases [PDF]

, 2003
Mathias Chamaillard, Dana J. Philpott, Stephen E. Girardin, Habib Zouali, Suzanne Lesage, Fabrice Chareyre, The Hung Bui, Marco Giovannini, Ulrich Zaehringer, Virginie Penard‐Lacronique, Philippe Sansonetti, Jean‐Pierre Hugot, Gilles Thomas   +12 more
openalex   +1 more source

Animal models of gene–environment interaction in schizophrenia: A dimensional perspective

Progress in neurobiology, 2016
Y. Ayhan, Ross McFarland, M. Pletnikov
semanticscholar   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

FEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik, Deniz Bakkalci, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

Gene-environment interaction study on the polygenic risk score for neuroticism, childhood adversity, and parental bonding. [PDF]

Personal Neurosci, 2023
Klingenberg B, Guloksuz S, Pries LK, Cinar O, Menne-Lothmann C, Decoster J, van Winkel R, Collip D, Delespaul P, De Hert M, Derom C, Thiery E, Jacobs N, Wichers M, Lin BD, Luykx J, van Os J, Rutten BPF.   +17 more
europepmc   +1 more source

Smoking, Genetic Polymorphisms in Biotransformation Enzymes, and Nonsyndromic Oral Clefting: A Gene-Environment Interaction

, 2001
Iris A.L.M. van Rooij, Manon J. M. Wegerif, Henny M. J. Roelofs, Wilbert H.M. Peters, Anne Marie Kuijpers‐Jagtman, Gerhard A. Zielhuis, Hans M.W.M. Merkus, Régine P.M. Steegers‐Theunissen   +7 more
openalex   +1 more source

Selection Bias in the Assessment of Gene-Environment Interaction in Case-Control Studies [PDF]

, 2003
L. M. Morimoto
openalex   +1 more source

Comparative single‐cell transcriptomic profiling of patient‐derived renal carcinoma cells in cellular and animal models of kidney cancer

FEBS Open Bio, EarlyView.
We generated and characterized clear cell renal cell carcinoma models using the patient‐derived RCC243 cell line—including cell culture, orthotopic, and metastatic tumors—via single‐cell RNA‐sequencing for comparisons between models and patient tumor datasets.
Richard Huang, Lynn Kee, Alexander Gont, Jalna Meens, Fraser G. Ferens, Meredith S. Irwin, Laurie Ailles, Scott A. Yuzwa, Claire M. Robinson, Michael Ohh   +9 more
wiley   +1 more source

The oxytocin receptor rs2254298 polymorphism and alcohol withdrawal symptoms: a gene-environment interaction in mood disorders. [PDF]

Front Psychiatry, 2023
Shen G, Yang S, Wu L, Chen Y, Hu Y, Zhou F, Wang W, Liu P, Wu F, Liu Y, Wang F, Chen L.   +11 more
europepmc   +1 more source