Results 231 to 240 of about 1,095,697 (331)

Statins induce monocytic differentiation in acute myeloid leukemia cells through the KLF4/DPYSL2A axis

FEBS Open Bio, EarlyView.
Statins, identified via the Comparative Toxicogenomics Database, promote monocytic differentiation and apoptosis in non‐APL AML cells by upregulating DPYSL2A through a KLF4‐dependent pathway. Mevalonate supplementation reversed these effects, indicating involvement of the mevalonate pathway.
Mina Noura, Kota Shoji, Michidai Nobe, Moe Ishikawa, Miu Tanaka, Akiko Okayama, Souichi Adachi, Hidemasa Matsuo   +7 more
wiley   +1 more source

Many roads to a gene-environment interaction. [PDF]

Am J Hum Genet
Westerman KE, Sofer T.
europepmc   +1 more source

Corrigendum: Gene-environment interaction in the era of precision medicine-filling the potholes rather than starting to build a new road. [PDF]

Front Genet, 2023
Álvarez-Castro JM.
europepmc   +1 more source

Evaluation of two methods for assessing gene‐environment interactions using data from the Danish case‐control study of facial clefts [PDF]

, 2005
Analee J. Etheredge, Kaare Christensen, Deborah del Junco, Jeffrey C. Murray, Laura E. Mitchell   +4 more
openalex   +1 more source

Microbial profile of the appendix niche in acute appendicitis: a novel sampling approach

FEBS Open Bio, EarlyView.
This study utilized a novel sampling method, ERAT (i.e. endoscopic retrograde appendicitis treatment)‐guided lumen aspiration, to obtain samples from the appendix, and shotgun metagenomic sequencing was performed for in situ characterization of the appendix microbiome in patients with acute appendicitis.
Huimin Ma, Mingfei Wang, Yanhu Feng, Wanqi Zhang, Wenbo Wang, Yanfeng Xie, Guixiang Kong, Jie Feng, Pengfei Wang, Qi Wang, Xiaojun Huang   +10 more
wiley   +1 more source

Genomic Insights into Dementia: Precision Medicine and the Impact of Gene-Environment Interaction. [PDF]

Aging Dis
Tripathi A, Pandey VK, Sharma G, Sharma AR, Taufeeq A, Jha AK, Kim JC.   +6 more
europepmc   +1 more source

Sleep Duration, Midday Napping, and Serum Homocysteine Levels: A Gene-Environment Interaction Study. [PDF]

Nutrients, 2023
Mo T, Wang Y, Gao H, Li W, Zhou L, Yuan Y, Zhang X, He M, Guo H, Long P, Wu T.   +10 more
europepmc   +1 more source

Transcriptional regulation of neuropeptide receptors underlies context‐dependent adaptation in Drosophila melanogaster

FEBS Open Bio, EarlyView.
Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu, Yanan Wei, Zekun Wu, Tianmu Zhang, DoHoon Lee, Hadi Najafi, Woo Jae Kim   +6 more
wiley   +1 more source

Gene-environment interaction in ADHD traits: the role of school environment, personality, callousness-unemotional traits and satisfaction with life. [PDF]

Eur Child Adolesc Psychiatry
Schwabe I, Pelt DHM, Greven CU.
europepmc   +1 more source

Gene-environment interaction explains a part of missing heritability in human body mass index. [PDF]

Commun Biol, 2023
Jung HU, Kim DJ, Baek EJ, Chung JY, Ha TW, Kim HK, Kang JO, Lim JE, Oh B.   +8 more
europepmc   +1 more source