Is there a folate‐related gene‐environment interaction in the etiology of childhood acute lymphoblastic leukemia? [PDF]
Elizabeth Milne+6 more
openalex +1 more source
We propose a context‐dependent model where the Duchenne muscular dystrophy (DMD) gene acts as a tumour suppressor in aggressive tumours and as an oncogene in less aggressive ones. We propose this model as a unified framework to explain the opposing survival associations with DMD expression and to guide experimental exploration of the dual role of DMD ...
Lee Machado+4 more
wiley +1 more source
Unveiling challenges in Mendelian randomization for gene-environment interaction. [PDF]
Gorfine M, Qu C, Peters U, Hsu L.
europepmc +1 more source
The effect of disease misclassification on the ability to detect a gene-environment interaction: implications of the specificity of case definitions for research on Gulf War illness. [PDF]
Haley RW, Dever JA, Kramer G, Teiber JF.
europepmc +1 more source
Gene-Environment Interactions: Paraoxonase (PON1) and Sensitivity to Organophosphate Toxicity [PDF]
Lucio G. Costa+2 more
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Structural and functional characterization of chitinase from carnivorous plant Drosera adelae
A class I chitinase from the carnivorous plant Drosera adelae was expressed and purified using a yeast system, revealing high enzymatic activity. Structural analyses of the catalytic and chitin‐binding domains identified key tyrosine residues involved in substrate binding, offering insights into the enzyme's adaptation for insect digestion.
Kazunari Yoneda+7 more
wiley +1 more source
Gene-Environment Interaction: Small Deletions (DELs) and Transcriptomic Profiles in Non-Melanoma Skin Cancer (NMSC) and Potential Implications for Therapy. [PDF]
Jasmine F+8 more
europepmc +1 more source
Gene–environment interactions and public health nutrition [PDF]
Marilyn Tseng
openalex +1 more source
Diffusion‐based size determination of solute particles: a method adapted for postsynaptic proteins
We present a diffusion‐based approach for measuring the size of macromolecules and their complexes, and demonstrate its use on postsynaptic proteins. The method requires fluorescein‐labelled protein samples, a microfluidic device that maintains laminar flow for said samples, a microscope recording the emitted fluorescent signals, and an analytic ...
András László Szabó+7 more
wiley +1 more source