Drought is one of the major threats to the maize yield especially in subtropical production systems. Understanding the genes and regulatory mechanisms of drought tolerance is important to sustain the yield.
Shikha Mittal +6 more
doaj +1 more source
Interaction between predisposing genes and environmental risk factors in cardiovascular disease: how prevention can counteract this salty combination [PDF]
Filippo Crea
openalex +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Growth Hormone Gene Polymorphism and Its Association with Partial Cumulative Milk Yields of Holstein Friesian Dairy Cattle [PDF]
Growth hormone gene (GH gene) plays an important role in regulating body growth and in developing mammary gland, similar with its interaction to specific receptors.
Andreas, E. (E) +3 more
core
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Cell Cycle Control Gene-Gene Interaction Model in Pregnancy Loss
Early stages of individual development are defined by active cell division and differentiation processes. Intercellular signaling molecules as well as proliferation control and DNA stabilizing factors act as basic functional groups.
Mashkina EV +3 more
doaj
Nature, Nurture and Egalitarian Policy: What Can We Learn from Molecular Genetics? [PDF]
This brief paper draws attention to molecular genetic research which may provide a new dimension to our understanding of how socioeconomic outcomes are generated. In particular, we provide an overview of the recently emerging evidence of gene-environment
Lundborg, Petter, Stenberg, Anders
core
Transcriptome-wide gene-gene interaction associations elucidate pathways and functional enrichment of complex traits. [PDF]
Evans LM +7 more
europepmc +1 more source
Interaction and functional interference of C / EBPβ with octamer factors in immunoglobulin gene transcription [PDF]
Eunice N. Hatada +2 more
openalex +1 more source
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source

