Results 111 to 120 of about 7,342,964 (293)

Feedback regulation of Ran gene expression by Ran protein

open access: yes, 2011
National Natural Science Foundation of China [30830084]; Hi-Tech Research and Development Program of China (863 program of China) [2010AA09Z403]; Ministry of Agriculture, China [201103034]; Chinese Universities Scientific FundRan, an abundant GTPase that
Wang, Jiajia   +3 more
core  

Towards more biological mutation operators in gene regulation studies [PDF]

open access: yes, 2003
Genetic regulation is often viewed as a complex system whose properties emerge from the interaction of regulatory genes. One major paradigm for studying the complex dynamics of gene regulation uses directed graphs to explore structure, behaviour and ...
Wiles, J.   +11 more
core   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

TLR Signaling Pathway Gene Polymorphisms, Gene–Gene and Gene–Environment Interactions in Allergic Rhinitis

open access: yesJournal of Inflammation Research, 2022
Ruo-Xi Chen,1,* Meng-Di Dai,1,* Qing-Zhao Zhang,1 Mei-Ping Lu,1 Mei-Lin Wang,2,3 Min Yin,1,4 Xin-Jie Zhu,1 Zhong-Fei Wu,1 Zheng-Dong Zhang,2,3 Lei Cheng1,4 1Department of Otorhinolaryngology & Clinical Allergy Center, The First Affiliated ...
Chen RX   +9 more
doaj  

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Gene-gene interaction: COLEC11 and MASP2 genotypes frequencies in patients with chronic CD and healthy controls.

open access: yes, 2019
Gene-gene interaction: COLEC11 and MASP2 genotypes frequencies in patients with chronic CD and healthy controls.
Iara J. Messias-Reason (535489)   +7 more
core   +1 more source

Testing Gene-Gene Interactions in the Case-Parents Design [PDF]

open access: yesHuman Heredity, 2011
The case-parents design has been widely used to detect genetic associations as it can prevent spurious association that could occur in population-based designs. When examining the effect of an individual genetic locus on a disease, logistic regressions developed by conditioning on parental genotypes provide complete protection from spurious association
openaire   +2 more sources

Characteristics of the phenotypes in prevalent and incident cases of heart failure in primary care: IBERICAN study

open access: yesBMC Primary Care
Background The management in primary care (PC) of the patients with Heart Failure (HF) is different from the management hospital, in a special way compared to cardiology departments.
Sergio Cinza-Sanjurjo   +9 more
doaj   +1 more source

Polymorphism in Genes Encoding HSP40 Family Proteins is Associated with Ischemic Stroke Risk and Brain Infarct Size: A Pilot Study

open access: yesJournal of Integrative Neuroscience
Background: Heat shock proteins (HSPs) play a critical role in the molecular mechanisms of ischemic stroke (IS). A possible role for HSP40 family proteins in atherosclerosis progression has already been revealed; however, to date ...
Ksenia A. Kobzeva   +5 more
doaj   +1 more source

Mechanisms of resistance to viruses

open access: yesPlant Protection Science, 2002
Resistance associated with a hypersensitive response (HR) and subsequent development of necrotic lesions (cell death) at the sites of virus infection can restrict virus movement in plants. Genes for HR are dominant and act on a gene-for-gene basis.
J.P.T. Valkonen
doaj   +1 more source

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