Cumulative Incidence in Monogenic Alzheimer's Disease and Frontotemporal Dementia: Gene-Gene Interaction Effect. [PDF]
Geviti A +23 more
europepmc +1 more source
Gene-Gene Interaction Analysis for the Survival Phenotype Based on the Kaplan-Meier Median Estimate. [PDF]
Park M, Lee JW, Park T, Lee S.
europepmc +1 more source
A discussion of gene–gene and gene–environment interactions and longitudinal genetic analysis of complex traits [PDF]
Ruzong Fan +2 more
openalex +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
PICDGI: A framework for predicting cancer driver genes through dynamic gene-gene interaction modeling of single-cell data. [PDF]
Atitey K, Anchang B.
europepmc +1 more source
NKCC1: A key regulator of glioblastoma progression
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source
Risk, resilience, and gene x environment interactions in rhesus monkeys
Suomi Stephen
openalex +1 more source
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
The Role of Gene-Gene Interaction Between <i>ADRA2A</i> and <i>SLC6A2</i> Polymorphisms in Attention System and Treatment Outcomes for Children with ADHD. [PDF]
Kang J, Choi BS, Kim B.
europepmc +1 more source

