Results 151 to 160 of about 5,255,551 (319)

Cross-Tissue Regulatory Gene Networks in Coronary Artery Disease [PDF]

, 2016
Husain A. Talukdar, Hassan Foroughi Asl, Rajeev Jain, Raili Ermel, Arno Ruusalepp, Oscar Franzén, Brian Kidd, Ben Readhead, Chiara Giannarelli, Jason C. Kovacic, Torbjörn Ivert, Joel T. Dudley, Mete Civelek, Aldons J. Lusis, Eric E. Schadt, Josefin Skogsberg, Tom Michoel, Johan Björkegren   +17 more
openalex   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

CENTRA: knowledge-based gene contextuality graphs reveal functional master regulators by centrality and fractality. [PDF]

NAR Genom Bioinform
Hause F, Wedler A, Keil R, Schian L, Glaß M, Grimm WF, Sorokin O, Hoehenwarter W, Sinz A, Hüttelmaier S.   +9 more
europepmc   +1 more source

The transcription factor CsbHLH18 of sweet orange functions in modulation of cold tolerance and homeostasis of reactive oxygen species by regulating the antioxidant gene [PDF]

, 2018
Jingjing Geng, Ji‐Hong Liu
openalex   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Short double-stranded RNA induces transcriptional gene silencing in human cancer cells in the absence of DNA methylation

, 2005
Angela H. Ting, Kornel E. Schuebel, James G. Herman, Stephen B. Baylin   +3 more
openalex   +1 more source

Genome-Wide Analysis Reveals Gene Expression and Metabolic Network Dynamics during Embryo Development in Arabidopsis   [PDF]

, 2011
Daoquan Xiang, Prakash Venglat, Chabane Tibiche, Hui Yang, Eddy Risseeuw, Yongguo Cao, Vivijan Babic, Mathieu Cloutier, W. A. Keller, Edwin Wang, Gopalan Selvaraj, Raju Datla   +11 more
openalex   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

Gene copy-number features generalize better than SNPs for antimicrobial resistance prediction in Staphylococcus aureus. [PDF]

NPJ Antimicrob Resist
Fistarol BF, Gervasio JD, Szöllősi GJ.
europepmc   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source