Results 191 to 200 of about 16,521,028 (347)

Knowledge mapping and bibliometric insights into gene therapy for rare inherited hematologic pathologies: focus on sickle cell disease, hemophilia, and thalassemia. [PDF]

Orphanet J Rare Dis
Sweileh MW.
europepmc   +1 more source

A CRISPRi-based genetic resource to study essential Staphylococcus aureus genes

, 2023
Patricia Reed, Moritz Sorg, Dominik Alwardt, Lúcia Serra, Helena Veiga, Simon Schäper, Mariana G. Pinho   +6 more
openalex   +1 more source

The Hole [PDF]

, 1993
Zeiger, Gene
core   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

LEP and FOXO1 genes, as a proposed tumor suppressor autophagic cell death related genes, can be targeted by antidiabetic therapy in nondiabetic breast cancer patients. [PDF]

Discov Oncol
Duran GA, Kiraz Y, Baykara D.
europepmc   +1 more source

A framework for modelling gene regulation which accommodates non-equilibrium mechanisms

, 2014
Tobias Ahsendorf, Felix Wong, Roland Eils, Jeremy Gunawardena   +3 more
openalex   +1 more source

Tumor‐agnostic detection of circulating tumor DNA in patients with advanced pancreatic cancer using targeted DNA methylation sequencing and cell‐free DNA fragmentomics

Molecular Oncology, EarlyView.
We evaluated circulating tumor DNA (ctDNA) detection in advanced pancreatic cancer using DNA methylation, cell‐free DNA fragment lengths, and 5′ end motifs. Machine learning models were trained to estimate ctDNA levels from each feature and their combination.
Morten Lapin, Kjersti Tjensvoll, Karin Hestnes Edland, Satu Oltedal, Herish Garresori, Bjørnar Gilje, Saga Ekedal, Trygve Eftestøl, Jan Terje Kvaløy, Filip Janku, Oddmund Nordgård   +10 more
wiley   +1 more source

Evolutionary Changes of <i>GT1</i> Provide Insights Into the Adaptation of Butterflies to Plant Feeding. [PDF]

Ecol Evol
Wu J, Yan H, Tang W, Li Z, Chakraborty A, He Z, Zhou C, He S.   +7 more
europepmc   +1 more source

Radicalization of Independence in Ukraine [PDF]

, 1991
Fishel, Gene
core   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source