Branch-specific gene discovery in cell differentiation using multi-omics graph attention. [PDF]
Yin Y, Zhuang L, Wang Y, Shi Y, Zhang B.
europepmc +1 more source
Moving Goods and People in International Commerce: Remarks of the Honorable Gene McNary [PDF]
McNary, Gene
core +1 more source
A bioinformatics screen identifies TCF19 as an aggressiveness‐sustaining gene in prostate cancer
Gene expression meta‐analysis in multiple prostate cancer patient cohorts identifies Transcription factor 19 (TCF19) as an aggressiveness‐sustaining gene with prognostic potential. TCF19 is a gene repressed by androgen signaling that sustains core cancer‐related processes such as vascular permeability or tumor growth and metastasis.
Amaia Ercilla +15 more
wiley +1 more source
CellSP enables module discovery and visualization for subcellular spatial transcriptomics data. [PDF]
Aggarwal B, Sinha S.
europepmc +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Spatial transcriptomic landscape and cellular neighborhood heterogeneity in cervical cancer: integrative single-cell and spatial RNA sequencing analysis. [PDF]
Mo D, Cao H, Lai S, Luo J, Ye W.
europepmc +1 more source
TCS: a computer program to estimate gene genealogies
M. Clement, D. Posada, K. Crandall
semanticscholar +1 more source
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source
Collectors, not hoarders: Complex gene structures in Amphidinium carterae revealed through nanopore sequencing. [PDF]
Judd M +4 more
europepmc +1 more source

