Results 271 to 280 of about 5,255,551 (319)
Some of the next articles are maybe not open access.
Songs of Genes, by Genes, for Genes
Leonardo, 2012The authors have defined a new concept of “base_position” and translated the protein-coding sequence to a sequence consisting of 12 base_positions. The authors developed a new algorithm for translating the base_position sequence to a melody with a range of at most a twelfth and without leaps larger than an octave, which should be turned upside-down by
Dongya Ge, Yixue Li
openaire +1 more source
Analysis of Gene‐Gene Interactions
Current Protocols in Human Genetics, 2017AbstractThe goal of this unit is to introduce epistasis, or gene‐gene interactions, as a significant contributor to the genetic architecture of complex traits, including disease susceptibility. This unit begins with an historical overview of the concept of epistasis and the challenges inherent in the identification of potential gene‐gene interactions ...
Brian S, Cole +4 more
openaire +2 more sources
Clinical Orthopaedics and Related Research, 2000
Gene therapy is the process whereby a therapeutic protein is synthesized from a DNA molecule (gene) that has been inserted into the cells. The goal is to produce the desired protein in the proper quantity in the proper location. Successful designing of vectors for gene therapy requires knowledge of gene structure and regulation.
openaire +2 more sources
Gene therapy is the process whereby a therapeutic protein is synthesized from a DNA molecule (gene) that has been inserted into the cells. The goal is to produce the desired protein in the proper quantity in the proper location. Successful designing of vectors for gene therapy requires knowledge of gene structure and regulation.
openaire +2 more sources
Royal Institute of Philosophy Supplement, 2005
Contrary to one possible interpretation of my title, this paper will not advocate any scepticism or ontological deflation. My concern will rather be with how we should best think about a realm of phenomena the existence of which is in no doubt, what has traditionally been referred to as the genetic.
openaire +1 more source
Contrary to one possible interpretation of my title, this paper will not advocate any scepticism or ontological deflation. My concern will rather be with how we should best think about a realm of phenomena the existence of which is in no doubt, what has traditionally been referred to as the genetic.
openaire +1 more source
Gene-Gene and Gene-Environment Interactions
2018Identifying gene-gene and gene-environment interactions may help us to better describe the genetic architecture for complex traits. While advances have been made in identifying genetic variants associated with complex traits through more dense panels of genetic variants and larger sample sizes, genome-wide interaction analyses are still limited in ...
openaire +2 more sources
Better Gene Expression by (-)Gene than by (+)Gene in Phage Gene Delivery Systems
Biotechnology Progress, 2006In recent years, capsid-modified filamentous bacteriophage has become a potential vector for gene delivery into mammalian cells. However, little was known about how the carried gene in the single-stranded genome expressed in mammalian cells. To explore whether the orientation of the carried gene affects its expression in the cells, we prepared EGF ...
Yun, Liang +6 more
openaire +2 more sources
Analysis of Gene‐Gene Interactions
Current Protocols in Human Genetics, 2003AbstractThe goal of this unit is to introduce gene‐gene interactions (epistasis) as a significant complicating factor in the search for disease susceptibility genes. This unit begins with an overview of gene‐gene interactions and why they are likely to be common.
openaire +3 more sources
Tandem genes and clustered genes
Journal of Theoretical Biology, 1995Two patterns of gene repetition are described: tandem arraying and clustering. Tandemly arrayed genes reside within segments of DNA that are repeated head-to-tail a number of times. Clustered genes are linked but irregularly spaced, are often mutually inverted in an unpredictable pattern and are connected by non-conserved DNA.
openaire +2 more sources