Androgen receptor polymorphisms and testicular cancer risk [PDF]
Testicular cancer (TC) is currently the most common malignant solid tumour in Caucasian males aged 15-39 years. Epidemiological evidence suggests that its onset may be due to an imbalance in the action of steroidal sex hormones and their receptors.
CARLINI, TANIA+9 more
core +1 more source
Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer+10 more
wiley +1 more source
Combining ability for seed yield and its components in sesame (Sesamum indicum L.)
Fifty sesame crosses generated in line x tester (10 lines x 5 testers) mating method were studied to estimate combining ability for fourteen characters in sesame.
M. B. Virani+4 more
doaj +1 more source
Identification of Newer Stable Genetic Sources for High Grain Number per Panicle and Understanding the Gene Action for Important Panicle Traits in Rice. [PDF]
Gunasekaran A+4 more
europepmc +1 more source
THE ACTION OF ALLELIC FORMS OF THE GENE A IN MAIZE. I. STUDIES OF VARIABILITY, DOSAGE AND DOMINANCE RELATIONS. THE DIVERGENT CHARACTER OF THE SERIES [PDF]
John R. Laughnan
openalex +1 more source
Yeast Features: Identifying Significant Features Shared Among Yeast Proteins for Functional Genomics [PDF]
Background High throughput yeast functional genomics experiments are revealing associations among tens to hundreds of genes using numerous experimental conditions.
Ashkan Golshani+8 more
core +1 more source
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican+7 more
wiley +1 more source
The correlation of substitution effects across populations and generations in the presence of nonadditive functional gene action. [PDF]
Legarra A+3 more
europepmc +1 more source
GENE ACTION AND POSITION EFFECT IN DUPLICATIONS IN DROSOPHILA MELANOGASTER [PDF]
F.J. Ratty
openalex +1 more source
Novel and unscrutinized immune entities of the zebrafish gut
Understudied cells of the zebrafish immune system include bona fide immune cells and epithelial (‐derived) cells with immune functions. Research focusing on zebrafish cells which demonstrate similarities to mammalian immune cell counterparts may help us understand the pathologies in which they are implicated. Currently available and advanced tools make
Audrey Inge Schytz Andersen‐Civil+5 more
wiley +1 more source