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siRNA: Mechanism of action, challenges, and therapeutic approaches.
European Journal of Pharmacology, 2021Owing to specific and compelling gene silencing, RNA interference (RNAi) is expected to become an essential approach in treating a variety of infectious, hemato-oncological, cardiovascular, and neurodegenerative conditions.
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Proceedings of the Royal Society of London. Series B. Biological Sciences, 1970
Abstract This paper deals with processes occurring in the assembly of genic products into cell organelles and structures, especially with processes determining the initiation, location, orientation and number of cortical structures in the ciliated protozoan, Paramecium aurelia.
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Abstract This paper deals with processes occurring in the assembly of genic products into cell organelles and structures, especially with processes determining the initiation, location, orientation and number of cortical structures in the ciliated protozoan, Paramecium aurelia.
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On Gene’s Action and Reciprocal Causation
Foundations of Science, 2010Advancing the reductionist conviction that biology must be in agreement with the assumptions of reductive physicalism (the upward hierarchy of causal powers, the upward fixing of facts concerning biological levels) A. Rosenberg argues that downward causation is ontologically incoherent and that it comes into play only when we are ignorant of the ...
Miquel, Paul-Antoine, Perovic, S.
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Visualization of Bacterial Genes in Action
Science, 1970The morphology of active structural and putative ribosomal RNA genes was observed by electron microscopy after lysis of fragile Escherichia coli cells. Conclusions drawn are: most of the chromosome is not genetically active at any one instant; translation is completely coupled with transcription; the 16 ...
O L, Miller, B A, Hamkalo, C A, Thomas
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