Results 241 to 250 of about 999,852 (312)

Integrated omics reveal a unique antibacterial mechanism of action for the small molecule HSI#6. [PDF]

Curr Res Microb Sci
Sedky H, Hamed MB, Vermeire K, Schymkowitz J, Karamanou S, Economou A.   +5 more
europepmc   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Cardiac Sodium Channel Regulation: A Potential New Therapeutic Target in Cardiomyopathy. [PDF]

Circ Res
Dudley SC.
europepmc   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

Experimental Platform for Screening and Validation of BacNa_v Gene Therapy Candidates. [PDF]

Circ Arrhythm Electrophysiol
Wu T, Nguyen HX, Siu YY, Li Y, Bursac N.
europepmc   +1 more source

THE DESCRIPTION AND ANALYSIS OF GENE ACTION AND INTERACTION

Cold Spring Harbor Symposia on Quantitative Biology, 1955
openaire   +2 more sources

Problems in the use of chemical and functional nomenclatures for steroids in human physiology, biology and pharmacology. [PDF]

RSC Adv
Honour JW.
europepmc   +1 more source

Norroa™ as a dsRNA biopesticide for <i>Varroa destructor</i>: insights from New Zealand research on mode of action, field efficacy, non-target effects, and social acceptance. [PDF]

Front Insect Sci
Lester PJ, Bulgarella M, Manley B, Masucci JD, McGruddy RA, Merk J, Narva K, Palmer S, Mercier OR, Smeele ZE.   +9 more
europepmc   +1 more source

Probing gene action during development

, 1987
Marx, Jean L.
core  

DNA-intercalating antiphage molecules trigger abortive infection through mutual destruction and synergize with bacterial immunity. [PDF]

Proc Natl Acad Sci U S A
Ernst L, Gätgens C, Rackow B, Pozhydaieva N, Gaaloul E, Krüger A, Seiffarth J, Bund M, Joisten-Rosenthal V, Kohlheyer D, Usadel B, Harms A, Höfer K, Frunzke J.   +13 more
europepmc   +1 more source