Assessment of genome annotation using gene function similarity within the gene neighborhood
BMC Bioinformatics, 2017 Background Functional annotation of bacterial genomes is an obligatory and crucially important step of information processing from the genome sequences into cellular mechanisms. However, there is a lack of computational methods to evaluate the quality of
Se-Ran Jun +3 more
doaj +1 more source
Comparison of hom(oe)ologous regions containing clusters of duplicated RGAs within Musa species and with rice [PDF]
, 2007 Understanding structure and evolution of genomic regions coding for proteins of agronomical interest is an important objective for crop improvement. We compare hom(oe)ologous regions within monocot genomes through BAC annotation.
Baurens, Franc-Christophe +11 more
core
Rad27/FEN1 prevents accumulation of Okazaki fragments and ribosomal DNA copy number changes
FEBS Letters, EarlyView.The budding yeast Rad27 is a structure‐specific endonuclease. Here, the authors reveal that Rad27 is crucial for maintaining the stability of the ribosomal RNA gene (rDNA) region. Rad27 deficiency leads to the accumulation of Okazaki fragments and changes in rDNA copy number.
Tsugumi Yamaji +3 more
wiley +1 more source
Vacuolar transport and function of Saccharomyces cerevisiae sterol ester hydrolase Tgl1
FEBS Letters, EarlyView.Tgl1, one of yeast sterol ester hydrolases, had been found on the lipid droplets where sterol esters are mainly stored. This study revealed that Tgl1 is transported into the vacuole depending on the ESCRT‐I–III complex, and that it exhibits intra‐vacuolar sterol ester hydrolase activity.
Takumi Nakatsuji +5 more
wiley +1 more source
The role of fibroblast growth factors in cell and cancer metabolism
FEBS Letters, EarlyView.Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley +1 more source
The Coffee Genome Hub : [W185] [PDF]
, 2014 The whole genome sequence of Coffea canephora, the perennial diploid species known as Robusta, has been recently obtained and portends to be published and released in the coming months.
Bocs, Stéphanie +7 more
core
An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots
FEBS Letters, EarlyView.This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino +7 more
wiley +1 more source
Unsupervised Classification for Tiling Arrays: ChIP-chip and Transcriptome
, 2011 Tiling arrays make possible a large scale exploration of the genome thanks to probes which cover the whole genome with very high density until 2 000 000 probes.
Aubourg, Sébastien +4 more
core +3 more sources
Combining gene prediction methods to improve metagenomic gene annotation
BMC Bioinformatics, 2011 Background Traditional gene annotation methods rely on characteristics that may not be available in short reads generated from next generation technology, resulting in suboptimal performance for metagenomic (environmental) samples.
Rosen Gail L, Yok Non G
doaj +1 more source
Visualizing Gene Ontology annotations
, 2016 to appear in the forthcoming book "The Gene Ontology Handbook" (Springer Humana, ISBN 978-1-4939-3741-7)
Supek, Fran, Škunca, Nives
openaire +2 more sources