Results 121 to 130 of about 7,510,778 (382)

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

The genome sequence and effector complement of the flax rust pathogen Melampsora lini [PDF]

open access: yes, 2016
Rust fungi cause serious yield reductions on crops, including wheat, barley, soybean, coffee, and represent real threats to global food security. Of these fungi, the flax rust pathogen Melampsora lini has been developed most extensively over the past 80 ...
Anderson, Claire   +9 more
core   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

ARMOUR – A Rice miRNA: mRNA Interaction Resource

open access: yesFrontiers in Plant Science, 2018
ARMOUR was developed as ARice miRNA:mRNA interaction resource. This informative and interactive database includes the experimentally validated expression profiles of miRNAs under different developmental and abiotic stress conditions across seven Indian ...
Neeti Sanan-Mishra   +5 more
doaj   +1 more source

GNPAnnot: a community annotation system applied to sugarcane sequences : W745 [PDF]

open access: yes, 2013
A large amount of data is being produced by current genome sequencing projects. Sequence annotations need to be organized into databases and widely accessible.
Bocs, Stéphanie   +6 more
core  

A quick guide for student-driven community genome annotation

open access: yes, 2018
High quality gene models are necessary to expand the molecular and genetic tools available for a target organism, but these are available for only a handful of model organisms that have undergone extensive curation and experimental validation over the ...
Benoit, Joshua B.   +10 more
core   +2 more sources

Coding exon-structure aware realigner (CESAR) utilizes genome alignments for accurate comparative gene annotation

open access: yesNucleic Acids Research, 2016
Identifying coding genes is an essential step in genome annotation. Here, we utilize existing whole genome alignments to detect conserved coding exons and then map gene annotations from one genome to many aligned genomes.
Virag Sharma, Anas Elghafari, M. Hiller
semanticscholar   +1 more source

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

The URGI plants and bio-agressors genomics annotation system [PDF]

open access: yes, 2009
The URGI genomic annotation platform, developed in the framework of the GnpAnnot project, relies on well known GMOD tools (http://gmod.org): Apollo, Chado and GBrowse.
Alaux, Michael   +8 more
core  

The SOL Genomics Network Model: Making Community Annotation Work [PDF]

open access: yes, 2009
The concept of community annotation is a growing discipline for achieving participation of the research community in depositing up‐to‐date knowledge in biological databases. The Solanaceae Genomics Network ("SGN":http ...
Adri Mills   +9 more
core   +2 more sources

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