Results 211 to 220 of about 547,402 (323)

GENCODE 2025: reference gene annotation for human and mouse. [PDF]

Nucleic Acids Res
Mudge JM, Carbonell-Sala S, Diekhans M, Martinez JG, Hunt T, Jungreis I, Loveland JE, Arnan C, Barnes I, Bennett R, Berry A, Bignell A, Cerdán-Vélez D, Cochran K, Cortés LT, Davidson C, Donaldson S, Dursun C, Fatima R, Hardy M, Hebbar P, Hollis Z, James BT, Jiang Y, Johnson R, Kaur G, Kay M, Mangan RJ, Maquedano M, Gómez LM, Mathlouthi N, Merritt R, Ni P, Palumbo E, Perteghella T, Pozo F, Raj S, Sisu C, Steed E, Sumathipala D, Suner MM, Uszczynska-Ratajczak B, Wass E, Yang YT, Zhang D, Finn RD, Gerstein M, Guigó R, Hubbard TJP, Kellis M, Kundaje A, Paten B, Tress ML, Birney E, Martin FJ, Frankish A.   +55 more
europepmc   +1 more source

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias, Ana Oitabén, Sonia Zumalave, Bernardo Rodriguez‐Martin, María Gallardo‐Gómez, Martín Santamarina, Ana Pequeño‐Valtierra, Laura Juaneda‐Magdalena, Ramón García‐Escudero, José Luis López‐Cedrún, Máximo Fraga, José M. C. Tubio, Mónica Martínez‐Fernández   +12 more
wiley   +1 more source

Statistical analysis of genomic protein family and domain controlled annotations for functional investigation of classified gene lists [PDF]

, 2007
Marco Masseroli, Elisa Bellistri, Andrea Franceschini, Francesco Pinciroli   +3 more
openalex   +1 more source

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

Molecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Chromosome-scale genome assembly and gene annotation of the Alligator Gar (Atractosteus spatula). [PDF]

Sci Data
Wang Q, Yu Q, Dong X, Chen H, Tian X, Qi P, Wu H, Yuan Y.   +7 more
europepmc   +1 more source

DAVID Knowledgebase: a gene-centered database integrating heterogeneous gene annotation resources to facilitate high-throughput gene functional analysis [PDF]

, 2007
Brad T. Sherman, Da Wei Huang, Qina Tan, Yongjian Guo, Stephan Bour, David Liu, R. Scott Stephens, Michael Baseler, H. Clifford Lane, Richard A. Lempicki   +9 more
openalex   +1 more source

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

Molecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach, Nilesh Chatterjee, Kellie Spahr, Gilberto Serrano de Almeida, Anabel Varela‐Carver, Taimur T. Shah, Mathias Winkler, Hashim U. Ahmed, Charlotte L. Bevan   +8 more
wiley   +1 more source

Identification of Cocconeis neothumensis var. marina using a polyphasic approach including ultrastructure and gene annotation. [PDF]

PLoS One
Somma E, Costantini M, Pennesi C, Ruocco N, De Castro O, Terlizzi A, Zupo V.   +6 more
europepmc   +1 more source

Comment on 'Hayai-Annotation Plants: an ultrafast and comprehensive functional gene annotation system in plants': the importance of taking the GO graph structure into account. [PDF]

Bioinformatics, 2021
Van Bel M, Vandepoele K.
europepmc   +1 more source

IDconverter and IDClight: Conversion and annotation of gene and protein IDs [PDF]

, 2007
Andreu Alibés, Patricio Yankilevich, Andrés Cañada, Ramón Díaz‐Uriarte   +3 more
openalex   +1 more source