Results 211 to 220 of about 566,833 (345)

Amplification of the Gene Ontology annotation of Affymetrix probe sets [PDF]

, 2006
Enrique M. Muro, Carolina Perez‐Iratxeta, Miguel A. Andrade‐Navarro   +2 more
openalex   +1 more source

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

Molecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha, Joana Pinheiro, Rui F. Marques, Patrícia Fontão, Diana Cardoso‐Carneiro, Adriana Mendes, Izabela N. F. Gomes, Ana Carolina Laus, Renato J. da Silva‐Oliveira, Rui Manuel Reis, Olga Martinho   +10 more
wiley   +1 more source

Decrypting cancer's spatial code: from single cells to tissue niches

Molecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik, Shi Pan, Eloise Withnell, Hou Wang Lam, Maria Secrier   +4 more
wiley   +1 more source

Chromosome-level assembly and gene annotation of Kappaphycus striatus genome. [PDF]

Sci Data
Zhou Z, Ma Y, Zhang J, Firdaus M, Roleda MY, Duan D.   +5 more
europepmc   +1 more source

The community-curated Pristionchus pacificus genome facilitates automated gene annotation improvement in related nematodes. [PDF]

BMC Genomics, 2021
Rödelsperger C.
europepmc   +1 more source

Comprehensive annotation of human bidirectional promoters identifies co-regulatory relationships among somatic breast and ovarian cancer genes

, 2005
Mary Qu Yang, Laura M. Koehly, Laura Elnitski   +2 more
openalex   +1 more source

DAVID Knowledgebase: a gene-centered database integrating heterogeneous gene annotation resources to facilitate high-throughput gene functional analysis [PDF]

, 2007
Brad T. Sherman, Da Wei Huang, Qina Tan, Yongjian Guo, Stephan Bour, David Liu, R. Scott Stephens, Michael Baseler, H. Clifford Lane, Richard A. Lempicki   +9 more
openalex   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

GENCODE 2025: reference gene annotation for human and mouse. [PDF]

Nucleic Acids Res
Mudge JM, Carbonell-Sala S, Diekhans M, Martinez JG, Hunt T, Jungreis I, Loveland JE, Arnan C, Barnes I, Bennett R, Berry A, Bignell A, Cerdán-Vélez D, Cochran K, Cortés LT, Davidson C, Donaldson S, Dursun C, Fatima R, Hardy M, Hebbar P, Hollis Z, James BT, Jiang Y, Johnson R, Kaur G, Kay M, Mangan RJ, Maquedano M, Gómez LM, Mathlouthi N, Merritt R, Ni P, Palumbo E, Perteghella T, Pozo F, Raj S, Sisu C, Steed E, Sumathipala D, Suner MM, Uszczynska-Ratajczak B, Wass E, Yang YT, Zhang D, Finn RD, Gerstein M, Guigó R, Hubbard TJP, Kellis M, Kundaje A, Paten B, Tress ML, Birney E, Martin FJ, Frankish A.   +55 more
europepmc   +1 more source

Uncovering transcriptional dark matter via gene annotation independent single-cell RNA sequencing analysis. [PDF]

Nat Commun, 2021
Wang MFZ, Mantri M, Chou SP, Scuderi GJ, McKellar DW, Butcher JT, Danko CG, De Vlaminck I.   +7 more
europepmc   +1 more source