Results 231 to 240 of about 7,510,778 (382)
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Long-read transcriptomics of a diverse human cohort reveals ancestry bias in gene annotation. [PDF]
Clavell-Revelles P +9 more
europepmc +1 more source
Integrative Functional Annotation of 52 Genetic Loci Influencing Myocardial Mass Identifies Candidate Regulatory Variants and Target Genes [PDF]
Daiane Hemerich +15 more
openalex +1 more source
Functional annotation of enzyme-encoding genes using deep learning with transformer layers
Gi Bae Kim +5 more
openalex +1 more source
BUSCO: assessing genome assembly and annotation completeness with single-copy orthologs
Felipe A. Simão +4 more
semanticscholar +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Reevaluating Human Gene Annotation: A Second-Generation Analysis of Chromosome 22 [PDF]
John Collins +8 more
openalex +1 more source

