Results 241 to 250 of about 547,402 (323)

Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management

Molecular Oncology, EarlyView.
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez, Asieh Naderi, Kim‐Tuyen Huynh‐Dam, Vitali Sikirzhytski, Ioulia Chatzistamou, Hippokratis Kiaris   +5 more
wiley   +1 more source

Paradigm shifts in the approaches for gene annotation [PDF]

Briefings in Bioinformatics, 2000
Jean-Jack M Riethoven, Juha Muilu, Thangavel Alphonse Thanaraj, Alan J. Robinson   +3 more
openaire   +3 more sources

Contigs directed gene annotation (ConDiGA) for accurate protein sequence database construction in metaproteomics. [PDF]

Microbiome
Wu E, Mallawaarachchi V, Zhao J, Yang Y, Liu H, Wang X, Shen C, Lin Y, Qiao L.   +8 more
europepmc   +1 more source

Transcript-level annotation of Affymetrix probesets improves the interpretation of gene expression data [PDF]

, 2007
Hui Yu, Feng Wang, Kang Tu, Lu Xie, Yuanyuan Li, Yixue Li   +5 more
openalex   +1 more source

Raphin‐1 mediates the survival and sensitivity to radiation of pediatric‐type diffuse high‐grade glioma via phosphorylated eukaryotic initiation factor 2α‐dependent and ‐independent processes

Molecular Oncology, EarlyView.
Raphin‐1 reduces the survival of PED‐DHGG cells and enhances their radiation sensitivity through both PeIF2α‐dependent and PeIF2α‐independent mechanisms. Raphin‐1 sustains elevated levels of PeIF2α, contributing to its PeIF2α‐dependent effects. Additionally, raphin‐1 interacts with CReP to mediate a separate radiosensitizing pathway that operates ...
Karin Eytan, Moshe Leitner, Amos Toren, Shoshana Paglin, Michal Yalon   +4 more
wiley   +1 more source

Illumina-based transcriptomic analysis of the fast-growing leguminous tree Acacia crassicarpa: functional gene annotation and identification of novel SSR-markers. [PDF]

Front Plant Sci
Ishio S, Kusunoki K, Nemoto M, Kanao T, Tamura T.   +4 more
europepmc   +1 more source

Proteotranscriptomics assisted gene annotation and spatial proteomics of Bombyx mori BmN4 cell line. [PDF]

BMC Genomics, 2020
Levin M, Scheibe M, Butter F.
europepmc   +1 more source

Plant Gene and Alternatively Spliced Variant Annotator. A Plant Genome Annotation Pipeline for Rice Gene and Alternatively Spliced Variant Identification with Cross-Species Expressed Sequence Tag Conservation from Seven Plant Species [PDF]

, 2007
Feng‐Chi Chen, Sheng‐Shun Wang, Shu‐Miaw Chaw, Yao‐Ting Huang, Trees‐Juen Chuang   +4 more
openalex   +1 more source

Targeting carbonic anhydrase IX/XII prevents the anti‐ferroptotic effect of stromal lactic acid in prostate carcinoma

Molecular Oncology, EarlyView.
In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella, Giuseppina Comito, Luigi Ippolito, Erica Pranzini, Marta Iozzo, Giulia Gangarossa, Francesca Virgilio, Silvia Bua, Alessio Nocentini, Giada Sandrini, Nicla Lorito, Marina Bacci, Gabriella Nesi, Pietro Spatafora, Sergio Serni, Claudiu T. Supuran, Andrea Morandi, Paola Chiarugi, Elisa Giannoni   +18 more
wiley   +1 more source

ToxCodAn-Genome: an automated pipeline for toxin-gene annotation in genome assembly of venomous lineages. [PDF]

Gigascience
Nachtigall PG, Durham AM, Rokyta DR, Junqueira-de-Azevedo ILM.   +3 more
europepmc   +1 more source