Results 251 to 260 of about 566,833 (345)

A bioinformatics screen identifies TCF19 as an aggressiveness‐sustaining gene in prostate cancer

Molecular Oncology, EarlyView.
Gene expression meta‐analysis in multiple prostate cancer patient cohorts identifies Transcription factor 19 (TCF19) as an aggressiveness‐sustaining gene with prognostic potential. TCF19 is a gene repressed by androgen signaling that sustains core cancer‐related processes such as vascular permeability or tumor growth and metastasis.
Amaia Ercilla, Jana R. Crespo, Saioa Garcia‐Longarte, Marta Fidalgo, Sara del Palacio, Natalia Martin‐Martin, Onintza Carlevaris, Ianire Astobiza, Sonia Fernández‐Ruiz, Marc Guiu, Laura Bárcena, Isabel Mendizabal, Ana M. Aransay, Mariona Graupera, Roger R. Gomis, Arkaitz Carracedo   +15 more
wiley   +1 more source

Improvements in viral gene annotation using large language models and soft alignments. [PDF]

BMC Bioinformatics
Harrigan WL, Ferrell BD, Wommack KE, Polson SW, Schreiber ZD, Belcaid M.   +5 more
europepmc   +1 more source

Involving Undergraduates in the Annotation and Analysis of Global Gene Expression Studies: Creation of a Maize Shoot Apical Meristem Expression Database [PDF]

, 2007
Brent Buckner, Jon Beck, Kate Browning, Ashleigh Fritz, Lisa Grantham, Eneda Hoxha, Zhian N. Kamvar, Ashley N. Lough, Olga Nikolova, Patrick S. Schnable, Michael J. Scanlon, Diane Janick‐Buckner   +11 more
openalex   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Contigs directed gene annotation (ConDiGA) for accurate protein sequence database construction in metaproteomics. [PDF]

Microbiome
Wu E, Mallawaarachchi V, Zhao J, Yang Y, Liu H, Wang X, Shen C, Lin Y, Qiao L.   +8 more
europepmc   +1 more source

Developmental stage annotation of Drosophila gene expression pattern images via an entire solution path for LDA [PDF]

, 2008
Jieping Ye, Jianhui Chen, Ravi Janardan, Sudhir Kumar   +3 more
openalex   +1 more source

Multi‐omic profiling of squamous cell lung cancer identifies metabolites and related genes associated with squamous cell carcinoma

Molecular Oncology, EarlyView.
Using multi‐omic characterization, we aimed to identify key regulators specific to squamous cell lung carcinoma (SqCC). SqCC‐specific differentially expressed genes were integrated with metabolics data. High expression of the creatine transporter SLC6A8, along with elevated creatine levels, appeared to be a distinct metabolic feature of SqCC.
Johan Staaf, Daniel Ehinger, Hans Brunnström, Mats Jönsson, Frida Rosengren, Marija Kotevska, Anna Karlsson, Mattias Aine, Christian Frezza, Maria Planck, Elsa Arbajian   +10 more
wiley   +1 more source

Illumina-based transcriptomic analysis of the fast-growing leguminous tree Acacia crassicarpa: functional gene annotation and identification of novel SSR-markers. [PDF]

Front Plant Sci
Ishio S, Kusunoki K, Nemoto M, Kanao T, Tamura T.   +4 more
europepmc   +1 more source

Proteotranscriptomics assisted gene annotation and spatial proteomics of Bombyx mori BmN4 cell line. [PDF]

BMC Genomics, 2020
Levin M, Scheibe M, Butter F.
europepmc   +1 more source

Gene ontology annotation as text categorization: An empirical study [PDF]

, 2008
Kazuhiro Seki, Javed Mostafa
openalex   +1 more source