Results 101 to 110 of about 754,180 (340)

Journal Staff [PDF]

, 2014
Background: The polytene nuclei of the dipteran Chironomus tentans (Ch. tentans) with their Balbiani ring (BR) genes constitute an exceptional model system for studies of the expression of endogenous eukaryotic genes.
Bjork, Petra, Giacomello, Stefania, Kutsenko, Alexey, Lundeberg, Joakim, Nystedt, Björn, Sonnhammer, Erik, Svensson, Thomas, Visa, Neus, Wieslander, Lars   +8 more
core   +2 more sources

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

ERASMUS: Efficient Remote Attestation via Self- Measurement for Unattended Settings

, 2017
Remote attestation (RA) is a popular means of detecting malware in embedded and IoT devices. RA is usually realized as an interactive protocol, whereby a trusted party -- verifier -- measures integrity of a potentially compromised remote device -- prover.
antonakakis, carpent, carpent, eldefrawy, ostrovsky, schellekens, stumpf, vijayan   +7 more
core   +1 more source

Strigolactones spatially influence lateral root development through the cytokinin signaling network [PDF]

, 2015
Strigolactones are important rhizosphere signals that act as phytohormones and have multiple functions, including modulation of lateral root (LR) development.
Beeckman, Tom, Boyer, François-Didier, De Cuyper, Carolien, De Keyser, Annick, Depuydt, Stephen, Goormachtig, Sofie, Jiang, Lingxiang, Marquez-Garcia, Belen, Matthys, Cedrick, Smet, Lien   +9 more
core   +3 more sources

Gene clustering pattern, promoter architecture, and gene expression stability in eukaryotic genomes [PDF]

Proceedings of the National Academy of Sciences, 2011
A balance between gene expression stability and evolvability is essential for the long-term maintenance of a living system. In this paper, we studied whether the genetic and epigenetic properties of the promoter affect gene expression variability. We hypothesized that upstream distance and orientation (head-to-head or head-to-tail) are important for ...
Yong H, Woo, Wen-Hsiung, Li
openaire   +2 more sources

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Chromatin architecture and gene expression in Escherichia coli.

Genome biology, 2004
Two recent genome-scale analyses underscore the importance of DNA topology and chromatin structure in regulating transcription in Escherichia coli.
Willenbrock, Hanni, Ussery, David
openaire   +3 more sources

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Evolution of Plant Architecture in Oryza Driven by the PROG1 Locus

Frontiers in Plant Science, 2020
The genetic control of plant architecture in crops is critical for agriculture and understanding morphological evolution. This study showed that an open reading frame (ORF) of the rice domestication gene PROG1 appeared 3.4–3.9 million years ago (Mya ...
Liyu Huang, Hui Liu, Hui Liu, Junjie Wu, Ruoping Zhao, Yanxia Li, Getachew Melaku, Getachew Melaku, Shilai Zhang, Guangfu Huang, Yachong Bao, Min Ning, Benjia Chen, Yurui Gong, Qingyi Hu, Jing Zhang, Yesheng Zhang, Yesheng Zhang   +17 more
doaj   +1 more source