Results 141 to 150 of about 322,007 (305)

3D Bioprinting of Thick Adipose Tissues with Integrated Vascular Hierarchies

Advanced Functional Materials, Volume 35, Issue 12, March 18, 2025.
An advanced 3D bioprinting technique is used here to create thick adipose tissues with a central, vessel and extensive branching. The construct is made using alginate, gelatin and collagen‐based bioinks. Flow through the complex vessel network is demonstrated as well as its successful integration with a femoral artery following implantation in a rat ...
Idit Goldfracht, Majd Machour, Inbal Michael, Maria Bulatova, Janette Zavin, Shulamit Levenberg   +5 more
wiley   +1 more source

Modeling of DNA local parameters predicts encrypted architectural motifs in Xenopus laevis ribosomal gene promoter

, 2000
Magali Roux-Rouquié
openalex   +1 more source

A Vascularized Microphysiological System Reproducing Endochondral Ossification in Vitro to Study Ewing Sarcoma Proliferation and Migration

Advanced Functional Materials, EarlyView.
A biofabricated 3D in vitro model recapitulating endochondral ossification (ECO) is described, mimicking the steps from condensation to chondrogenesis and hypertrophy, culminating with vascularization of the hypertrophic construct. As a model proof of concept application, Ewing Sarcoma cells are seeded in the model, showing modifications in their ...
Maria Vittoria Colombo, Chiara Arrigoni, Tobias Faehling, Antonietta Verrillo, Viviana Secci, Thomas G. P. Grünewald, Giuseppe Talò, Alexandra Kummer, Jorge Gonzalez, Vincenzo De Rosa, Christian Candrian, Andrea Barbero, Florencia Cidre‐Aranaz, Matteo Moretti   +13 more
wiley   +1 more source

Large Grain 2, an NHL Domain-Containing Protein, Interacts with FUWA and Regulates Plant Architecture and Grain Size Through the Brassinosteroid Signaling Pathway in Rice

Rice
Plant architecture and grain size are critical traits for rice breeding. Brassinosteroid (BR), a class of plant hormones, regulates these traits by modulating cell elongation, division, and differentiation.
Zhengyan Xu, Jierui Zeng, Xiaorong Zhou, Yang Liu, Feifan Chen, Haitang Liu, Xiao Peng, Zhengqi Han, Feihong Hou, Hao Wang, Weilan Chen, Bin Tu, Ting Li, Jiawei Xiong, Zhaohui Zhong, Yuping Wang, Bingtian Ma, Peng Qin, Shigui Li, Hua Yuan   +19 more
doaj   +1 more source

Architecture of the Replication Fork Stalled at the 3′ End of Yeast Ribosomal Genes

, 2000
Markus Gruber, Ralf Erik Wellinger, José M. Sogo   +2 more
openalex   +1 more source

Architectural Arrangement of Cloned Proximal Sequence Element-Binding Protein Subunits on Drosophila U1 and U6 snRNA Gene Promoters [PDF]

, 2004
Cheng Li, Gale A. Harding, Jason Robert Parise, Kathleen J. McNamara-Schroeder, William E. Stumph   +4 more
openalex   +1 more source

Gene dosage architecture across complex traits

Long AbstractCopy number variants (CNVs) have large effects on complex traits, but they are rare and remain challenging to study. As a result, our understanding of biological functions linking gene dosage to complex traits remains limited, and whether these functions sensitive to gene dosage are similar to those underlying the effects of rare single ...
Kazem, Sayeh, Kumar, Kuldeep, Jean-Louis, Martineau, Huguet, Guillaume, Renne, Thomas, Saci, Zohra, Engchuan, Worrawat, Shanta, Omar, Thiruvahindrapuram, Bhooma, MacDonald, Jeffrey R., Greenwood, Celia M. T., Scherer, Stephen W., Almasy, Laura, Sebat, Jonathan, Glahn, David C, Dumas, Guillaume, Jacquemont, Sébastien   +16 more
openaire   +2 more sources

Bioorthogonal Engineering of Cellular Microenvironments Using Isonitrile Ligations

Advanced Functional Materials, EarlyView.
Highly selective chemistries are required for fabrication and post‐cross–linking modification of cell‐encapsulating hydrogels used in tissue engineering applications. Isonitrile ligation reactions represent a promising class of bioorthogonal chemistries for engineering hydrogel‐based cellular microenvironments. Isonitrile‐based hydrogels are stable and
Ping Zhou, Lauren Brown, Christopher M. Madl   +2 more
wiley   +1 more source

Methyl CpG binding proteins: coupling chromatin architecture to gene regulation

, 2001
Paul A. Wade
openalex   +1 more source

Photothermal Hydrogel with Mn3O4 Nanoparticles Alleviates Intervertebral Disc Degeneration by Scavenging ROS and Regulating Extracellular Matrix Metabolism

Advanced Functional Materials, EarlyView.
The MPTT‐nanozyme‐hydrogel system (Mn3O4@ChS‐HA) provides a multifunctional therapeutic strategy for intervertebral disc degeneration (IVDD), effectively targeting oxidative stress and enhancing AF repair by restoring extracellular matrix (ECM) and redox homeostasis.
Yangyang Chen, Chan Xue, Feifei Ni, Binwu Hu, Miaoheng Yan, He Zhang, Yuxiang Hu, Xiaoyao Peng, Guangfang Li, Yu Han, Hongjian Liu, Zengwu Shao, Qin Wang, Yulong Wei   +13 more
wiley   +1 more source