Results 11 to 20 of about 754,180 (340)
Editorial: Chromatin architecture in gene regulation and disease
Frontiers in Genetics, 2023 Xiang Wang
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PARP1 Regulates Circular RNA Biogenesis though Control of Transcriptional Dynamics
Cells, 2023 Circular RNAs (circRNAs) are a recently discovered class of RNAs derived from protein-coding genes that have important biological and pathological roles.
Rebekah Eleazer +6 more
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Frontiers in Plant Science, 2021 The papain-like cysteine proteases (PLCPs) are the most abundant family of cysteine proteases in plants, with essential roles in biotic/abiotic stress responses, growth and senescence.
Yanlei Zhai +5 more
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Frontiers in Molecular Biosciences, 2021 An evolutionarily conserved feature of introns is their ability to enhance expression of genes that harbor them. Introns have been shown to regulate gene expression at the transcription and post-transcription level.
Katherine Dwyer +3 more
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Architectural limits on split genes [PDF]
Proceedings of the National Academy of Sciences, 1996 Exon/intron architecture varies across the eukaryotic kingdom with large introns and small exons the rule in vertebrates and the opposite in lower eukaryotes. To investigate the relationship between exon and intron size in pre-mRNA processing, internally expanded exons were placed in vertebrate genes with small and large introns.
D A, Sterner, T, Carlo, S M, Berget
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Gene architectures that minimize cost of gene expression [PDF]
Molecular Cell, 2017 Gene expression burdens cells by consuming resources and energy. While numerous studies have investigated regulation of expression level, little is known about gene design elements that govern expression costs. Here, we ask how cells minimize production costs while maintaining a given protein expression level and whether there are gene architectures ...
Idan, Frumkin +9 more
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Promoter architectures and developmental gene regulation [PDF]
Seminars in Cell & Developmental Biology, 2016 Core promoters are minimal regions sufficient to direct accurate initiation of transcription and are crucial for regulation of gene expression. They are highly diverse in terms of associated core promoter motifs, underlying sequence composition and patterns of transcription initiation.
Vanja Haberle, Boris Lenhard
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Cluster J Mycobacteriophages: Intron Splicing in Capsid and Tail Genes [PDF]
, 2013 Bacteriophages isolated on Mycobacterium smegmatis mc2155 represent many distinct genomes sharing little or no DNA sequence similarity. The genomes are architecturally mosaic and are replete with genes of unknown function.
Best, AA +17 more
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Scientific Reports, 2021 Neolamarckia cadamba is an important tropical and subtropical tree for timber industry in southern China and is also a medicinal plant because of the secondary product cadambine. N. cadamba belongs to Rubiaceae family and its taxonomic relationships with
Xi Wang +5 more
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Deafness: from genetic architecture to gene therapy
Nature Reviews Genetics, 2023 Progress in deciphering the genetic architecture of human sensorineural hearing impairment (SNHI) or loss, and multidisciplinary studies of mouse models, have led to the elucidation of the molecular mechanisms underlying auditory system function, primarily in the cochlea, the mammalian hearing organ.
Petit, Christine +2 more
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