Frontiers in Genetics, 2012 The intron-exon architecture of many eukaryotic genes raises the intriguing question of whether this unique organization serves any function, or is it simply a result of the spread of functionless introns in eukaryotic genomes.
Liran eCarmel +2 more
doaj +1 more source
Frontiers in Plant Science, 2022 The Cellulose synthase superfamily synthesizes cellulose and different hemicellulosic polysaccharides in plant cell walls. While much has been discovered about the evolution and function of these genes, their genomic architecture and relationship with ...
Francesco Pancaldi +3 more
doaj +1 more source
Mapping the genetic architecture of gene expression in human liver [PDF]
, 2008 Genetic variants that are associated with common human diseases do not lead directly to disease, but instead act on intermediate, molecular phenotypes that in turn induce changes in higher-order disease traits.
Avila-Campillo, I +30 more
core +3 more sources
Pericentromeric heterochromatin is hierarchically organized and spatially contacts H3K9me2 islands in euchromatin. [PDF]
, 2020 Membraneless pericentromeric heterochromatin (PCH) domains play vital roles in chromosome dynamics and genome stability. However, our current understanding of 3D genome organization does not include PCH domains because of technical challenges associated ...
Acevedo, David +7 more
core +3 more sources
Predicting gene expression in the human malaria parasite Plasmodium falciparum using histone modification, nucleosome positioning, and 3D localization features. [PDF]
, 2019 Empirical evidence suggests that the malaria parasite Plasmodium falciparum employs a broad range of mechanisms to regulate gene transcription throughout the organism's complex life cycle.
Cook, Kate +4 more
core +2 more sources
Implications of Rewiring Bacterial Quorum Sensing [PDF]
, 2008 Bacteria employ quorum sensing, a form of cell-cell communication, to sense changes in population density and regulate gene expression accordingly.
Arnold, Frances H., Haseltine, Eric L.
core +4 more sources
Gene expression homeostasis and chromosome architecture [PDF]
BioArchitecture, 2014 In rapidly growing populations of bacterial cells, including those of the model organism Escherichia coli, genes essential for growth--such as those involved in protein synthesis--are expressed at high levels; this is in contrast to many horizontally-acquired genes, which are maintained at low transcriptional levels. (1) This balance in gene expression
openaire +2 more sources
cpSNP discovery and genotyping for a Pinus taeda breeding population with targeted comparison to related conifers [PDF]
PeerJPinus taeda (Loblolly pine) is the most important commercial tree species in the southern United States and a significant non-native plantation species in China. Its genetic improvement program has been implemented in South China for 30 years.
Ling Wang +9 more
doaj +2 more sources
CFVisual: an interactive desktop platform for drawing gene structure and protein architecture
BMC Bioinformatics, 2022 Background When researchers perform gene family analysis, they often analyze the structural characteristics of the gene, such as the distribution of introns and exons.
Huilong Chen +4 more
doaj +1 more source
On tower and checkerboard neural network architectures for gene expression inference
BMC Genomics, 2020 Background One possible approach how to economically facilitate gene expression profiling is to use the L1000 platform which measures the expression of ∼1,000 landmark genes and uses a computational method to infer the expression of another ∼10,000 genes.
Vladimír Kunc, Jiří Kléma
doaj +1 more source