Results 41 to 50 of about 322,007 (305)
Frontiers in Plant Science, 2022 The Cellulose synthase superfamily synthesizes cellulose and different hemicellulosic polysaccharides in plant cell walls. While much has been discovered about the evolution and function of these genes, their genomic architecture and relationship with ...
Francesco Pancaldi +3 more
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Deafness: from genetic architecture to gene therapy
Nature Reviews Genetics, 2023 Progress in deciphering the genetic architecture of human sensorineural hearing impairment (SNHI) or loss, and multidisciplinary studies of mouse models, have led to the elucidation of the molecular mechanisms underlying auditory system function, primarily in the cochlea, the mammalian hearing organ.
Petit, Christine +2 more
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cpSNP discovery and genotyping for a Pinus taeda breeding population with targeted comparison to related conifers [PDF]
PeerJPinus taeda (Loblolly pine) is the most important commercial tree species in the southern United States and a significant non-native plantation species in China. Its genetic improvement program has been implemented in South China for 30 years.
Ling Wang +9 more
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The Dynamic Architecture of Hox Gene Clusters
Science, 2011 Sequential activation of Hox genes correlates with a transition of negative to positive three-dimensional chromosome structure.
Noordermeer +10 more
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On tower and checkerboard neural network architectures for gene expression inference
BMC Genomics, 2020 Background One possible approach how to economically facilitate gene expression profiling is to use the L1000 platform which measures the expression of ∼1,000 landmark genes and uses a computational method to infer the expression of another ∼10,000 genes.
Vladimír Kunc, Jiří Kléma
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Architecture of a Yeast U6 RNA Gene Promoter [PDF]
Molecular and Cellular Biology, 1993 The promoters of vertebrate and yeast U6 small nuclear RNA genes are structurally dissimilar, although both are recognized by RNA polymerase III. Vertebrate U6 RNA genes have exclusively upstream promoters, while the U6 RNA gene from the yeast Saccharomyces cerevisiae (SNR6) has internal and downstream promoter elements that match the tRNA gene ...
David A. Brow +3 more
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Corruption of the intra-gene DNA methylation architecture is a hallmark of cancer. [PDF]
PLoS ONE, 2013 Epigenetic processes--including DNA methylation--are increasingly seen as having a fundamental role in chronic diseases like cancer. It is well known that methylation levels at particular genes or loci differ between normal and diseased tissue.
Thomas E Bartlett +5 more
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The constrained architecture of mammalian Hox gene clusters [PDF]
Proceedings of the National Academy of Sciences, 2019 In many animal species with a bilateral symmetry, Hox genes are clustered either at one or at several genomic loci. This organization has a functional relevance, as the transcriptional control applied to each gene depends upon its relative position within the gene cluster. It was previously noted that vertebrate
Lucille Lopez-Delisle +8 more
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Theoretical principles of transcription factor traffic on folded chromatin
Nature Communications, 2018 How transcription factors find their targets in vivo is still poorly understood. Here the authors use molecular dynamics simulations to investigate how transcription factors diffuse on chromatin, providing a theoretical framework for understanding the ...
Ruggero Cortini, Guillaume J. Filion
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Turkish Journal of Agriculture: Food Science and Technology, 2018 The traditional fermented food consumption has become very popular because of the increasing public concern about food additives. Lactic Acid Bacteria (LAB) species have traditionally been used as starter cultures in the production of fermented food. LAB
Yekta Gezginç +3 more
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