Results 81 to 90 of about 322,007 (305)
mBio, 2019 Ciliates, a eukaryotic clade that is over 1 billion years old, are defined by division of genome function between transcriptionally inactive germline micronuclei and functional somatic macronuclei.
Ying Yan +4 more
doaj +1 more source
Mapping the Genetic Architecture of Gene Regulation in Whole Blood [PDF]
PLoS ONE, 2014 We aimed to assess whether whole blood expression quantitative trait loci (eQTLs) with effects in cis and trans are robust and can be used to identify regulatory pathways affecting disease susceptibility.We performed whole-genome eQTL analyses in 890 participants of the KORA F4 study and in two independent replication samples (SHIP-TREND, N = 976 and ...
Schramm, Katharina +28 more
openaire +7 more sources
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Microbial BiotechnologyThis Lilliput article provides a literature overview on ecological effects of the plant microbiome with a focus on practical application in forestry, agriculture and urban greenspace under the spectre of climate change.
Felix Brüssow +2 more
doaj +1 more source
Interspecific Hybridization Barrier Between Paeonia ostii and P. ludlowii
PlantsPaeonia ludlowii is a threatened and valuable germplasm in the cultivated tree peony gene pool, with distinctive traits such as tall stature, pure yellow flowers, and scarlet foliage in autumn.
Yingzi Guo +5 more
doaj +1 more source
The gene–environmental architecture of the development of adolescent substance use [PDF]
Psychological Medicine, 2018 AbstractBackgroundUsing a longitudinal twin design and a latent growth curve/autoregressive approach, this study examined the genetic–environmental architecture of substance use across adolescence.MethodsSelf-reports of substance use (i.e. alcohol, marijuana) were collected at ages 13, 14, 15, and 17 years from 476 twin pairs (475 boys, 477 girls ...
Vitaro, F +5 more
openaire +3 more sources
FEBS Letters, EarlyView.Phototrophs evolved light‐harvesting systems adapted for efficient photon capture in habitats enriched in far‐red radiation. A subset of eukaryotic pigment‐binding proteins can absorb far‐red photons via low‐energy chlorophyll states known as red forms.
Antonello Amelii +8 more
wiley +1 more source
Haspin kinase modulates nuclear architecture and Polycomb-dependent gene silencing.
PLoS Genetics, 2020 Haspin, a highly conserved kinase in eukaryotes, has been shown to be responsible for phosphorylation of histone H3 at threonine 3 (H3T3ph) during mitosis, in mammals and yeast.
Ujué Fresán +4 more
doaj +1 more source
Looping mediated interaction between the promoter and 3' UTR regulates type II collagen expression in chondrocytes. [PDF]
PLoS ONE, 2012 Type II collagen is the major component of articular cartilage and is mainly synthesized by chondrocytes. Repeated sub-culturing of primary chondrocytes leads to reduction of type II collagen gene (Col2a1) expression, which mimics the process of ...
Arijita Jash +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser +11 more
wiley +1 more source