Results 31 to 40 of about 8,793,913 (366)
Stem Cell Reports, 2016 Induced pluripotent stem cells (iPSCs) represent an innovative source for the standardized in vitro generation of macrophages (Mφ). We here describe a robust and efficient protocol to obtain mature and functional Mφ from healthy as well as disease ...
Adele Mucci +13 more
doaj +1 more source
antiSMASH 4.0—improvements in chemistry prediction and gene cluster boundary identification
Nucleic Acids Res., 2017 Many antibiotics, chemotherapeutics, crop protection agents and food preservatives originate from molecules produced by bacteria, fungi or plants. In recent years, genome mining methodologies have been widely adopted to identify and characterize the ...
K. Blin +17 more
semanticscholar +1 more source
Clustering Genes of Common Evolutionary History [PDF]
Molecular Biology and Evolution, 2016 accepted at Molecular Biology and ...
Gori Kevin +4 more
openaire +6 more sources
Identification of PKS-NRPS Hybrid Metabolites in Marine-Derived Penicillium oxalicum
Marine Drugs, 2022 Filamentous fungi are abundant resources of bioactive natural products. Here, 151 marine-derived fungi were collected from the north Yellow Sea and identified by an internal transcribed spacer (ITS) sequence.
Hongcheng Li +9 more
doaj +1 more source
Identification of a novel botulinum neurotoxin gene cluster in Enterococcus
FEBS Letters, 2018 The deadly neurotoxins of Clostridium botulinum (BoNTs) comprise eight serotypes (A–G; X). The neurotoxin gene cluster encoding BoNT and its accessory proteins includes an operon containing an ntnh gene upstream of the boNT gene.
J. Brunt +3 more
semanticscholar +1 more source
Lost in translation: pluripotent stem cell‐derived hematopoiesis
EMBO Molecular Medicine, 2015 Pluripotent stem cells (PSCs) such as embryonic stem cells or induced pluripotent stem cells represent a promising cell type to gain novel insights into human biology.
Mania Ackermann +3 more
doaj +1 more source
Proceedings of the National Academy of Sciences of the United States of America, 2018 Significance Evolutionary and comparative genomics, combined with reverse genetics, have the power to identify and characterize new biology. Here, we use these approaches in several nontraditional model species of budding yeasts to characterize a budding
David J Krause +10 more
semanticscholar +1 more source
Frontiers in Microbiology, 2023 Glycoside hydrolases (GHs) are carbohydrate-active enzymes essential for many environmental (e.g., carbon cycling) and biotechnological (e.g., biofuels) processes.
Renaud Berlemont
doaj +1 more source
Frontiers in Microbiology, 2018 Milk and dairy products are rich in nutrients and are therefore habitats for various microbiomes. However, the composition of nutrients can be quite diverse, in particular among the sulfur containing amino acids.
Daniel Wüthrich +5 more
doaj +1 more source
Minimum Information about a Biosynthetic Gene cluster.
Nature Chemical Biology, 2015 A wide variety of enzymatic pathways that produce specialized metabolites in bacteria, fungi and plants are known to be encoded in biosynthetic gene clusters.
M. Medema +153 more
semanticscholar +1 more source