Results 41 to 50 of about 9,738,594 (396)
Minimum Information about a Biosynthetic Gene cluster.
Nature Chemical Biology, 2015 A wide variety of enzymatic pathways that produce specialized metabolites in bacteria, fungi and plants are known to be encoded in biosynthetic gene clusters.
M. Medema +153 more
semanticscholar +1 more source
Toxins, 2019 Phytotoxins, secondary metabolites toxic to plants and produced by fungi, are believed to play an important role in disease development by targeting host cellular machineries and/or interfering with host immune responses. The Ascochyta blight diseases on
Wonyong Kim, Weidong Chen
doaj +1 more source
Frontiers in Marine Science, 2022 Mangroves are extreme inter-tidal environments containing rich microbial communities. Actinobacteria from mangroves have an unprecedented ability to biosynthesize secondary metabolites.
Dini Hu +4 more
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Regulation of Secondary Metabolism by the Velvet Complex Is Temperature-Responsive in Aspergillus
G3: Genes, Genomes, Genetics, 2016 Sensing and responding to environmental cues is critical to the lifestyle of filamentous fungi. How environmental variation influences fungi to produce a wide diversity of ecologically important secondary metabolites (SMs) is not well understood.
Abigail L. Lind +4 more
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Evolutionary Histories of Type III Polyketide Synthases in Fungi
Frontiers in Microbiology, 2020 Type III polyketide synthases (PKSs) produce secondary metabolites with diverse biological activities, including antimicrobials. While they have been extensively studied in plants and bacteria, only a handful of type III PKSs from fungi has been ...
Jorge Carlos Navarro-Muñoz +1 more
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Genetics of Dothistromin Biosynthesis of Dothistroma septosporum: An Update
Toxins, 2010 Dothistroma needle blight is one of the most devastating fungal pine diseases worldwide. The disease is characterized by accumulation in pine needles of a red toxin, dothistromin, that is chemically related to aflatoxin (AF) and sterigmatocystin (ST ...
Rosie E. Bradshaw, Arne Schwelm
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Journal of Fungi, 2022 Genome comparison between the maize pathogens Ustilago maydis and Sporisorium reilianum revealed a large diversity region (19-1) containing nearly 30 effector gene candidates, whose deletion severely hampers virulence of both fungi.
Yulei Zhao +9 more
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Triggering the expression of a silent gene cluster from genetically intractable bacteria results in scleric acid discovery [PDF]
, 2019 In this study, we report the rapid characterisation of a novel microbial natural product resulting from the rational derepression of a silent gene cluster.
Alberti, Fabrizio +5 more
core +1 more source
Cloning and Heterologous Expression of the Grecocycline Biosynthetic Gene Cluster
PLoS ONE, 2016 Transformation-associated recombination (TAR) in yeast is a rapid and inexpensive method for cloning and assembly of large DNA fragments, which relies on natural homologous recombination.
O. Bilyk +3 more
semanticscholar +1 more source
Mutational analysis of a phenazine biosynthetic gene cluster in Streptomyces anulatus 9663
Beilstein Journal of Organic Chemistry, 2012 The biosynthetic gene cluster for endophenazines, i.e., prenylated phenazines from Streptomyces anulatus 9663, was heterologously expressed in several engineered host strains derived from Streptomyces coelicolor M145.
Orwah Saleh +6 more
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