Results 281 to 290 of about 8,692,782 (389)

Cell Membrane Vesicle Camouflaged Artificial Cells

open access: yesAdvanced Functional Materials, EarlyView.
Artificial cells camouflaged with a cell membrane vesicle coating are able to assemble into synthetic aggregates that exhibit rudimentary communication capabilities. Additionally, when these artificial cells are equipped with antioxidant capabilities, they are able to protect the intracellular homeostasis in HepG2 cells present in semi‐synthetic ...
Paula De Dios Andres   +11 more
wiley   +1 more source

Adeno-associated virus vector as a platform for gene therapy delivery

open access: yesNature reviews. Drug discovery, 2019
Dan Wang, P. Tai, G. Gao
semanticscholar   +1 more source

H2O2‐Generating Advanced Nanomaterials for Cancer Treatment

open access: yesAdvanced Functional Materials, EarlyView.
H2O2‐generating nanoplatforms can exploit tumor redox imbalance for O2 and toxic reactive oxygen species generation, leading to hypoxia reversal, and apoptosis of cancer cells, respectively. This review highlights the mechanisms of these nanoplatforms, including exogenous H₂O₂ delivery, endogenous amplification, and metal peroxides, which leads to ...
Kiyan Musaie   +8 more
wiley   +1 more source

Alleviation of Aging‐Related Hallmarks in a Mouse Model of Progeria via a Nanoparticle‐Based Artificial Transcription Factor

open access: yesAdvanced Functional Materials, EarlyView.
Oct4‐nanoscript, a biomimetic nanoparticle‐based artificial transcription factor, precisely regulates cellular rejuvenation by activating Oct4 target genes, restoring epigenetic marks, and reducing DNA damage. In a progeria model, it effectively rescued aging‐associated pathologies and extended lifespan.
Hongwon Kim   +8 more
wiley   +1 more source

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