\u3cem\u3eAnolis\u3c/em\u3e Sex Chromosomes Are Derived from A Single Ancestral Pair [PDF]
, 2014 To explain the frequency and distribution of heteromorphic sex chromosomes in the lizard genus Anolis, we compared the relative roles of sex chromosome conservation versus turnover of sex‐determining mechanisms. We used model‐based comparative methods to
Gamble, Tony +3 more
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Expression of ribosomal protein genes cloned in a hybrid plasmid in Escherichia coli: gene dosage effects on synthesis of ribosomal proteins and ribosomal protein messenger ribonucleic acid [PDF]
, 1979 Ann M. Fallon +3 more
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Learning Counterfactual Representations for Estimating Individual Dose-Response Curves
, 2019 Estimating what would be an individual's potential response to varying levels of exposure to a treatment is of high practical relevance for several important fields, such as healthcare, economics and public policy.
Bauer, Stefan +4 more
core +1 more source
Regulation of enzyme activities inDrosophila: I. The detection of regulatory loci by gene dosage responses [PDF]
, 1974 John M. Rawls, John C. Lucchesi
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Molecular Oncology, EarlyView.TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach +8 more
wiley +1 more source
Gene Dosage for 5 S Ribosomal Ribonucleic Acid in Escherichia coli and Bacillus megaterium [PDF]
, 1971 B Pace, Norman R. Pace
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Molecular Oncology, EarlyView.Non‐small cell lung cancer targeted treatment is limited to a few known genetic alterations, with few alternatives in advanced treatment lines. To direct treatment decisions by drug sensitivity testing (DST), this study compared several methods for tumor cell isolation from malignant effusions, pointing to repeated CD45+ cell depletion for effective ...
Navit Mooshayef +10 more
wiley +1 more source
GENE DOSAGE AND THE EXPRESSION OF ELECTROPHORETIC PATTERNS IN HETEROPLOID MOUSE CELL LINES [PDF]
, 1973 Rosann A. Farber
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Molecular Oncology, EarlyView.Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon +13 more
wiley +1 more source
Gene dosage: evidence for assignment of erythrocyte acid phosphatase locus to chromosome 2. [PDF]
, 1975 R.E. Magenis +5 more
openalex +1 more source