Results 251 to 260 of about 7,162,706 (382)
Sequential Multilocus Fluorescence In Situ Hybridization Can Detect Complex Patterns of Increased Gene Dosage at the Single Cell Level in Tissue Sections [PDF]
, 2001 Axel Walch +9 more
openalex +1 more source
Advanced Biology, EarlyView.A detailed workflow for recombinant GALC production and characterization is presented to support enzyme replacement therapy for Krabbe disease. In vitro assays demonstrate that physiological GALC doses restore enzymatic activity and autophagic flux without affecting cell viability, whereas higher doses impair autophagy and reduce viability.
Ambra Del Grosso +5 more
wiley +1 more source
3D Bioprinting of Thick Adipose Tissues with Integrated Vascular Hierarchies
Advanced Functional Materials, Volume 35, Issue 12, March 18, 2025.An advanced 3D bioprinting technique is used here to create thick adipose tissues with a central, vessel and extensive branching. The construct is made using alginate, gelatin and collagen‐based bioinks. Flow through the complex vessel network is demonstrated as well as its successful integration with a femoral artery following implantation in a rat ...
Idit Goldfracht +5 more
wiley +1 more source
GENE DOSAGE RELATIONS FOR HAPLOIDS AND DIPLOIDS OF HABROBRACON [PDF]
Genetics, 1951 Arnold M. Clark, C. J. Mitchell
openaire +3 more sources
Correction: Increased gene dosage of RFWD2 causes autistic-like behaviors and aberrant synaptic formation and function in mice. [PDF]
Mol PsychiatryLi YX +9 more
europepmc +1 more source
Reduced gene dosage is a common mechanism of neuropathologies caused by ATP6AP2 splicing mutations. [PDF]
Parkinsonism Relat Disord, 2022 Edelman WC +8 more
europepmc +1 more source
Advanced Functional Materials, EarlyView.This study introduces an extracorporeal hemoperfusion system incorporating porous microbeads embedded with autocatalytic ceria nanoparticles (CeNPs) for targeted reactive oxygen species (ROS) scavenging in septic shock. The blood‐compatible hemoperfusion cartridge demonstrated significant improvements in survival, hemodynamic stability, and organ ...
Pilseon Im +10 more
wiley +1 more source
Advanced Functional Materials, EarlyView.Joule‐assisted nanotherapeutic urethral stent harnesses a smart, biodegradable magnesium stent to orchestrate spatiotemporal theragenerative therapy for urethral strictures. Magnetically induced Joule heating enables on‐demand drug release and bacterial ablation, while simultaneously guiding urothelial regeneration.
Yuhyun Na +15 more
wiley +1 more source