Sequence-Specific Targeting of Drosophila roX Genes by the MSL Dosage Compensation Complex [PDF]
Yongkyu Park+6 more
openalex +1 more source
Electric Pulse Regulated MXene Based Nanozymes for Integrative Bioelectricity Immuno‐Cancer Therapy
MXenzyme‐mediated bioelectricity cancer therapy (MXenzyme‐BECT) enhances cancer cell death through irreversible depolarization, ion channel disruption, ROS generation, and immunogenic cell death. Computational simulations reveal the electrical mechanisms by which MXenzyme acts on single cells and support to predict treatment parameters. Next‐generation
Sanghee Lee+6 more
wiley +1 more source
Quantitative real-time PCR for gene dosage determinations in microdeletion genotypes [PDF]
Jonathan Covault+3 more
openalex +1 more source
Cell Membrane Vesicle Camouflaged Artificial Cells
Artificial cells camouflaged with a cell membrane vesicle coating are able to assemble into synthetic aggregates that exhibit rudimentary communication capabilities. Additionally, when these artificial cells are equipped with antioxidant capabilities, they are able to protect the intracellular homeostasis in HepG2 cells present in semi‐synthetic ...
Paula De Dios Andres+11 more
wiley +1 more source
H2O2‐Generating Advanced Nanomaterials for Cancer Treatment
H2O2‐generating nanoplatforms can exploit tumor redox imbalance for O2 and toxic reactive oxygen species generation, leading to hypoxia reversal, and apoptosis of cancer cells, respectively. This review highlights the mechanisms of these nanoplatforms, including exogenous H₂O₂ delivery, endogenous amplification, and metal peroxides, which leads to ...
Kiyan Musaie+8 more
wiley +1 more source
Effects of gene dosage and development on subcortical nuclei volumes in individuals with 22q11.2 copy number variations. [PDF]
Schleifer CH+9 more
europepmc +1 more source
Increased gene dosage ofInk4a/Arfresults in cancer resistance and normal aging [PDF]
Ander Matheu+7 more
openalex +1 more source
Targeting PI3K/Akt/mTOR signaling in rodent models of PMP22 gene-dosage diseases. [PDF]
Krauter D+12 more
europepmc +1 more source
Generation of Two Distinct Functional Isoforms of Dosage-Sensitive Sex Reversal-Adrenal Hypoplasia Congenita-Critical Region on the X Chromosome Gene 1 (DAX-1) by Alternative Splicing [PDF]
Anwar Hossain+2 more
openalex +1 more source