Results 81 to 90 of about 519,971 (295)
InsectsPopulation replacement refers to the process by which a wild-type population of insect pests is replaced by a population possessing modified traits or abilities.
Yu Zhao +4 more
doaj +1 more source
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
A Y-chromosome shredding gene drive for controlling pest vertebrate populations
eLife, 2019 Self-replicating gene drives that modify sex ratios or infer a fitness cost could be used to control populations of invasive alien species. The targeted deletion of Y sex chromosomes using CRISPR technology offers a new approach for sex bias that could ...
Thomas AA Prowse +4 more
doaj +1 more source
The legal regulation of gene drive technologies
, 2021 Gene drive technologies purport to provide a panacea and yet in doing so present unprecedented risks that threaten to change, potentially irreversibly, the way in which we live in the world.
Elves, Charlotte
core +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Modelling Allee effects in a transgenic mosquito population during range expansion
Journal of Biological Dynamics, 2019 Mosquitoes are vectors for many diseases that cause significant mortality and morbidity. As mosquito populations expand their range, they may undergo mate-finding Allee effects such that their ability to successfully reproduce becomes difficult at low ...
Melody Walker +3 more
doaj +1 more source
Genetic Biocontrol for Invasive Species
Frontiers in Bioengineering and Biotechnology, 2020 Invasive species are increasingly affecting agriculture, food, fisheries, and forestry resources throughout the world. As a result of global trade, invasive species are often introduced into new environments where they become established and cause harm ...
John L. Teem +14 more
doaj +1 more source
Conditions for Investment in Genetic Biocontrol of Pest Vertebrates in Australia
Frontiers in Agronomy, 2022 Managing pest vertebrate species in Australia is a significant challenge for government, industry, research sectors and land-managers. Innovative tools such as genetic biocontrol offers decision-makers a potentially effective means of reducing the impact
Lucy Carter +16 more
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Evaluating Gene Drive Approaches for Public Benefit
, 2020 Gene drive approaches—those which bias inheritance of a genetic element in a population of sexually reproducing organisms—have the potential to provide important public benefits.
Santos, Michael R., Michael R. Santos
core +1 more source