Results 71 to 80 of about 3,726,105 (294)
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
A Y-chromosome shredding gene drive for controlling pest vertebrate populations
eLife, 2019 Self-replicating gene drives that modify sex ratios or infer a fitness cost could be used to control populations of invasive alien species. The targeted deletion of Y sex chromosomes using CRISPR technology offers a new approach for sex bias that could ...
Thomas AA Prowse +4 more
doaj +1 more source
Gene regulated car driving: using a gene regulatory network to drive a virtual car [PDF]
Genetic Programming and Evolvable Machines, 2014 This paper presents a virtual racing car controller based on an artificial gene regulatory network. Usually used to control virtual cells in developmental models, recent works showed that gene regulatory networks are also capable to control various kinds of agents such as foraging agents, pole cart, swarm robots, etc.
Stéphane Sanchez, Sylvain Cussat-Blanc
openaire +4 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Modelling Allee effects in a transgenic mosquito population during range expansion
Journal of Biological Dynamics, 2019 Mosquitoes are vectors for many diseases that cause significant mortality and morbidity. As mosquito populations expand their range, they may undergo mate-finding Allee effects such that their ability to successfully reproduce becomes difficult at low ...
Melody Walker +3 more
doaj +1 more source
Genetic Biocontrol for Invasive Species
Frontiers in Bioengineering and Biotechnology, 2020 Invasive species are increasingly affecting agriculture, food, fisheries, and forestry resources throughout the world. As a result of global trade, invasive species are often introduced into new environments where they become established and cause harm ...
John L. Teem +14 more
doaj +1 more source
Gene drive communication: exploring experts’ lived experience of metaphor use
New Genetics and Society, 2022 Metaphors have been crucial in making genetics and genomics public, from the code and the book of life to genetic scissors and gene surgery. A new field is emerging called “gene drive” – a range of controversial technologies that can potentially be used ...
Brigitte Nerlich, Aleksandra Stelmach
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Conditions for Investment in Genetic Biocontrol of Pest Vertebrates in Australia
Frontiers in Agronomy, 2022 Managing pest vertebrate species in Australia is a significant challenge for government, industry, research sectors and land-managers. Innovative tools such as genetic biocontrol offers decision-makers a potentially effective means of reducing the impact
Lucy Carter +16 more
doaj +1 more source
Combining gene drive with mass drug administration.
, 2022 (A) 35% reduction in mean worm burden (MWB) is observed in 10 years with gene drive alone. (B) Targeted administration of MDA at 60% annual reduction (efficacy*coverage) in MWB results in more rapid but temporary reduction than the use of gene drive ...
Chloe G. Rickards (14035038) +5 more
core +1 more source