Results 101 to 110 of about 11,418,435 (287)
Genomically informed gene drive modelling
, 2022 © 2022 Benjamin James CammCRISPR/Cas gene drives are a focus of genetic biocontrol for pest species. They have the potential to radically affect pest species, by making them more manageable or by eradicating them.
Camm, Benjamin James
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Modular Linear-Drive Cryocooler Electronics
, 2008 Presented at the 16th International Cryocooler Conference, held May 17-20, 2008 in Atlanta, Georgia.The Modular Advanced Cryocooler Electronics (MACE) system developed at Iris Technology Corporation combines configurable, high-power motor drives with ...
Jackson, M. A. +4 more
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Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
The Effect of Mating Complexity on Gene Drive Dynamics
, 2023 Verma P, Reeves RG, Simon S, Otto M, Gokhale CS. The Effect of Mating Complexity on Gene Drive Dynamics. The American Naturalist. 2023;201(1):E1-E22.**Abstract** Gene drive technology promises to deliver on some of the global challenges humanity faces to-
Simon, Samson +4 more
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FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Taming Parasites by Tailoring Them
Frontiers in Cellular and Infection Microbiology, 2017 The next-generation gene editing based on CRISPR (clustered regularly interspaced short palindromic repeats) has been successfully implemented in a wide range of organisms including some protozoan parasites.
Bingjian Ren, Nishith Gupta
doaj +1 more source
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
FEBS Letters, EarlyView.Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
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BMC BiologyBackground Invasive management strategies range from preventing new invasive species incursions to eliminating established populations, with all requiring effective monitoring to guide action.
Antoinette J. Piaggio +6 more
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