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Preservation of duplicate genes by originalization
Genetica, 2008Neofunctionalization, subfunctionalization and increasing gene dosage were proposed to be the possible ways to explain duplicate-gene preservation in previous studies. However, in some natural populations, such as yeast Saccharomyces cerevisiae, a considerable proportion of the duplicate genes originated from ancient whole genomic duplication (WGD) is ...
Cheng Xue, Yunxin Fu, Yunxin Fu
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Gene Duplication and the Evolution of Enzymes
Nature, 1968The relationship between structure and function of proteins makes it unlikely that a new enzyme activity can evolve unless the genome contains extra DNA with suitable coding properties such as is provided by the duplication of a gene for a functionally related enzyme.
R. L. Watts, David C. Watts
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Evidence for gene duplication in collagen
Journal of Molecular Biology, 1976The amino acid sequence of collagen α 1 chain has been compared with itself at various displacements to search for systematic and significant repeats. It shows regularities at intervals related to the stagger between adjacent triple-helical molecules in the fibril, at a distance D of 670 A or 78 (Gly-X-Y) triplets.
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Role of gene duplication in evolution
Genome, 1989It is now known that many multigene and supergene families exist in eukaryote genomes: multigene families with uniform copy members like genes for ribosomal RNA, those with variable members like immunoglobulin genes, and supergene families such as those for various growth factor and hormone receptors.
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Seminars in Cell & Developmental Biology, 1999
The study of Hox gene clusters continues to serve as a paradigm for those interested in vertebrate genome evolution. Recent exciting discoveries about Hox gene composition in fishes challenges conventional views about vertebrate Hox gene evolution, and has initiated lively debates concerning the evolutionary events making the divergence of the major ...
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The study of Hox gene clusters continues to serve as a paradigm for those interested in vertebrate genome evolution. Recent exciting discoveries about Hox gene composition in fishes challenges conventional views about vertebrate Hox gene evolution, and has initiated lively debates concerning the evolutionary events making the divergence of the major ...
openaire +2 more sources