Results 311 to 320 of about 325,097 (348)

Preservation of duplicate genes by originalization

Genetica, 2008
Neofunctionalization, subfunctionalization and increasing gene dosage were proposed to be the possible ways to explain duplicate-gene preservation in previous studies. However, in some natural populations, such as yeast Saccharomyces cerevisiae, a considerable proportion of the duplicate genes originated from ancient whole genomic duplication (WGD) is ...
Cheng Xue, Yunxin Fu, Yunxin Fu
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Gene Duplication and the Evolution of Enzymes

Nature, 1968
The relationship between structure and function of proteins makes it unlikely that a new enzyme activity can evolve unless the genome contains extra DNA with suitable coding properties such as is provided by the duplication of a gene for a functionally related enzyme.
R. L. Watts, David C. Watts
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Evidence for gene duplication in collagen

Journal of Molecular Biology, 1976
The amino acid sequence of collagen α 1 chain has been compared with itself at various displacements to search for systematic and significant repeats. It shows regularities at intervals related to the stagger between adjacent triple-helical molecules in the fibril, at a distance D of 670 A or 78 (Gly-X-Y) triplets.
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Horizontal gene transfers as metagenomic gene duplications

Molecular BioSystems, 2012
While it is well accepted that horizontal gene transfer plays an important role in the evolution and the diversification of prokaryotic genomes, many questions remain open regarding its functional mechanisms of action and its interplay with the extant genome.
Marco Cosentino Lagomarsino, Marco Cosentino Lagomarsino, Luigi Grassi, Martin J. Lercher, Michele Caselle   +4 more
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Role of gene duplication in evolution

Genome, 1989
It is now known that many multigene and supergene families exist in eukaryote genomes: multigene families with uniform copy members like genes for ribosomal RNA, those with variable members like immunoglobulin genes, and supergene families such as those for various growth factor and hormone receptors.
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Hox gene duplication in fish

Seminars in Cell & Developmental Biology, 1999
The study of Hox gene clusters continues to serve as a paradigm for those interested in vertebrate genome evolution. Recent exciting discoveries about Hox gene composition in fishes challenges conventional views about vertebrate Hox gene evolution, and has initiated lively debates concerning the evolutionary events making the divergence of the major ...
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Quantifying gene duplication

Nature Reviews Genetics, 2022
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Cancer epigenetics in clinical practice

Ca-A Cancer Journal for Clinicians, 2023
Veronica Davalos, Manel Esteller
exaly  

Systemic therapy for hormone receptor‐positive/human epidermal growth factor receptor 2‐negative early stage and metastatic breast cancer

Ca-A Cancer Journal for Clinicians, 2023
Laura A Huppert, Hope S Rugo
exaly  

Gene duplications in H. influenzae [PDF]

Nature, 1995
Brenner, S E, Hubbard, T, Murzin, A, Chothia, C   +3 more
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