Results 71 to 80 of about 3,440,639 (300)

GENE DUPLICATION AND PHYLOGENY IN CLARKIA [PDF]

Evolution, 1979
Direct evidence for the descent of a group of species from a single common ancestor is rarely possible in the absence of fossils. Consequently, phylogenetic taxonomy relies on comparative analysis of morphological, chromosomal, and biochemical characters for evidence of relationship.
L D, Gottlieb, N F, Weeden
openaire   +2 more sources

Evolution after gene duplication : Models, mechanisms, sequences, systems, and organisms

, 2007
Gene duplication is postulated to have played a major role in the evolution of biological novelty. Here, gene duplication is examined across levels of biological organization in an attempt to create a unified picture of the mechanistic process by which ...
Rastogi, Shruti, Dittmar, Katharina, Arvestad, Lars,, Roth, Christian, Light, Sara, Ekman, Diana, Liberles, David A., Ekman, Diana,, Roth, Christian,, Light, Sara,, Arvestad, Lars, Lars Arvestad, Diana Ekman, Sara Light, David A. Liberles, Katharina Dittmar, Shruti Rastogi, Christian Roth   +17 more
core   +1 more source

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

Molecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan, Beatriz Martín‐Gracia, Eva Bassols‐Citores, Krizia Sagini, Maria K. Andersen, Tuula A. Nyman, May‐Britt Tessem, Morten B. Rye, Alicia Llorente   +8 more
wiley   +1 more source

Insight into transcription factor gene duplication from Caenorhabditis elegans Promoterome-driven expression patterns [PDF]

, 2007
Background The C. elegans Promoterome is a powerful resource for revealing the regulatory mechanisms by which transcription is controlled pan-genomically.
Shingles, Jane, Denis Dupuy, Vidal Marc, Reece-Hoyes, John S., Walhout, Albertha JM, Jane Shingles, Hope, Ian A., Albertha JM Walhout, Grove, Christian A., Hope, Ian A, Christian A Grove, Walhout Albertha JM, Grove Christian A, Reece-Hoyes, John S, Shingles Jane, Grove, Christian A, Walhout, Albertha J M, Dupuy, Denis, Hope Ian A, Vidal, Marc, Reece-Hoyes John S, John S Reece-Hoyes, Marc Vidal, Ian A Hope, Dupuy Denis   +24 more
core   +1 more source

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

Molecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara, Kosuke Murakami, Shiro Takamatsu, Akiko Kanto, Seiichi Mori, Tomoyuki Otani, Kazuko Sakai, Yasushi Kotani, Kazuto Nishio, Kaoru Abiko, Noriomi Matsumura   +10 more
wiley   +1 more source

The desaturase gene family : an evolutionary study of putative speciation genes in 12 species of Drosophila [PDF]

, 2012
The formation and persistence of species are the subject of much debate among biologists. Many species of Drosophila are behaviourally isolated, meaning that heterospecific individuals are not attracted to one another and do not interbreed.
Keays, Maria C.
core   +2 more sources

Gene Duplication and Ectopic Gene Conversion in Drosophila [PDF]

Genes, 2011
The evolutionary impact of gene duplication events has been a theme of Drosophila genetics dating back to the Morgan School. While considerable attention has been placed on the genetic novelties that duplicates are capable of introducing, and the role that positive selection plays in their early stages of duplicate evolution, much less attention has ...
Arguello, J. Roman, Connallon, Tim
openaire   +2 more sources

Evolution signatures in genome network properties [PDF]

, 2011
Genomes maybe organized as networks where protein-protein association plays the role of network links. The resulting networks are far from being random and their topological properties are a consequence of the underlying mechanisms for genome evolution ...
Rodrigo Dalmolin, Mauro Castro, Ricardo Ferreira, José Luiz Rybarczyk-Filho, Rita de Almeida, Jose Claudio Moreira, Leonardo Brunnet   +6 more
core  

Duplication of centromeric histone H3 (HTR12) gene in Arabidopsis halleri and A-lyrata, plant species with multiple centromeric satellite sequences [PDF]

, 2006
Arabidopsis halleri and lyrata have three different major centromeric satellite sequences, a unique finding for a diploid Arabidopsis species. Since centromeric histones coevolve with centromeric satellites, these proteins would be predicted to show ...
A. Kawabe, S. Nasuda, Kawabe, Akira, Nasuda, Shuhei, D. Charlesworth, Charlesworth, Deborah   +5 more
core   +1 more source

Overcoming platinum resistance by the disulfiram metabolite CuET in novel preclinical models of human carcinomas

Molecular Oncology, EarlyView.
Cisplatin‐resistant cancer cells survive DNA‐damaging platinum‐based treatment yet remain sensitive to CuET‐induced proteotoxic stress. The distinct mechanism of action allows CuET to overcome and eliminate cisplatin‐resistant tumour cells, unless highly expressed metallothioneins (MTs) interfere with CuET, thereby highlighting MT levels as candidate ...
Stefanos Arampatzis, Tereza Buchtová, Jirina Bartkova, Marie Lund Bay, Christoffer Lynge Halvorsen, Zuzana Machacova, Zdenek Skrott, Martin Mistrik, Ekaterina Dulina, Miguel Andujar‐Sanchez, Estrid Høgdall, Tine Henrichsen Schnack, Claus Høgdall, Berit Jul Mosgaard, Marie Boennelycke, Jacob Brink Laursen, Allan Jensen, Susanne K. Kjær, Tuula Kallunki, Robert Strauss, Jiri Bartek   +20 more
wiley   +1 more source