Results 141 to 150 of about 2,669,754 (369)

Micro-Vesicles of Moringa oleifera Seeds in Heterozygous Rats for DAT Gene: Effects of Oral Intake on Behavioral Profile and Hematological Parameters. [PDF]

Int J Environ Res Public Health, 2021
Buccheri C, Festucci F, Potestà M, Roglia V, Bernardini R, Minutolo A, Montesano C, Adriani W.   +7 more
europepmc   +1 more source

Decision letter for "The CB1R rs2023239 receptor gene variant significantly affects the reinforcing effects of nicotine, but not cue reactivity, in human smokers"

, 2020

openalex   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Effects of dopamine on leptin release and leptin gene (OB) expression in adipocytes from obese and hypertensive patients

, 2013
Cleto Alvarez-Aguilar,1–3 Alfonso Rafael Alvarez-Paredes,2 Bengt Lindholm,4 Peter Stenvinkel,4 Elvia García-López,4 Oliva Mejía-Rodríguez,5 Joel Edmundo López-Meza,6 Dante Amato,7 Ramon Paniagua8 1Hospital General
Alvarez-Aguilar C, Mejía-Rodríguez O, Alvarez-Paredes AR, Amato D, López-Meza JE, Paniagua R, Lindholm B, Stenvinkel P, García-López E   +8 more
core  

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Cataloguing the Effects of Genetic Variants in 5' Upstream Regions of Eicosanoid Related Genes [PDF]

, 2015
James R. Perkins, J.A. Cornejo‐García, Inmaculada Doña, Natalia Blanca‐López, María del Carmen Plaza‐Seron, Juan A. G. Ranea, Veronique Godineau, Cristobalina Mayorga, Marı́a José Torres, Gabriela Cantó, Miguel Blanca   +10 more
openalex   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Effects of oocyte maturation regimen on the relative abundance of gene transcripts in bovine blastocysts derived in vitro or in vivo [PDF]

, 2002
H. Knijn
openalex   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source