Results 281 to 290 of about 2,669,754 (369)

Environmental effects on stunting and the expression of a tiller inhibition ( tin ) gene in wheat

, 2002
B. L. Duggan, Richard A. Richards, Hiroshi Tsuyuzaki   +2 more
openalex   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Pharmacogenomics and Epigenetic Regulation Transforming Pediatric Precision Therapeutics. [PDF]

J Pers Med
Satyam SM, Prabhakar S, Densil T, Mohammed HT, Kumari R, El-Tanani M, Rehman A, Kharoufeh A, Dalbah M, Eltrabishi MTZM.   +9 more
europepmc   +1 more source

The effects of rebamipide-based gene-expression analysis in human conjunctival epithelial cells

, 2018
Keiko Yamada, Mayumi Ueta, Hiromi Nishigaki, Norihiko Yokoi, Chie Sotozono, Shigeru Kinoshita   +5 more
openalex   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

<i>Lacticaseibacillus casei</i> and <i>Lacticaseibacillus rhamnosus</i> cell-free supernatants induce apoptosis-related responses in PANC-1 human pancreatic cancer cells. [PDF]

Iran J Microbiol
Moradi S, Moradi-Hajidavaloo R, Soleimanifar F, Shahzamani K, Hajian M, Mansouri-Tehrani HA.   +5 more
europepmc   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Regional and size-dependent effects of ambient agricultural particulate matter on Ah-receptor activity and inflammatory responses in human U937 macrophages. [PDF]

Inhal Toxicol
Li X, Chengcheng J, Zhang C, Lin Q, D'Evelyn SM, Clark T, Bein KJ, Zhang Q, Lundberg A, Kado S, Connolly JC, Haarmann-Stemmann T, Niedek CR, He Y, Li W, Pinkerton KE, Vogel CFA.   +16 more
europepmc   +1 more source

Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis

Molecular Oncology, EarlyView.
LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini, Maria Caterina Mione   +1 more
wiley   +1 more source

Advances in the Gene-Diet Interactions and Human Health. [PDF]

Nutrients
Antunes LMG.
europepmc   +1 more source