Results 321 to 330 of about 2,669,754 (369)
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Predicting the effects of gene deletion
ACM SIGKDD Explorations Newsletter, 2002In this paper, we describe techniques that can be used to predict the effects of gene deletion. We will focus mainly on the creation of predictive variables, and then briefly discuss different modeling techniques that have been used successfully on this data.
David S. Vogel, Randy C. Axelrod
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Effects of glucocorticoids on gene transcription
European Journal of Pharmacology, 2004Glucocorticoids bind to and activate a cytoplasmic glucocorticoid receptor. The activated glucocorticoid receptor translocates into the nucleus and binds to specific response elements in the promoter regions of anti-inflammatory genes such as lipocortin-1 and secretory leukocyte protease inhibitor (SLPI). However, the major anti-inflammatory effects of
Ryuji, Hayashi +3 more
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Effects of Insulin on Gene Transcription
Annual Review of Physiology, 1989for these changes in mRNA concentration. The steady-state concentration of a messenger RNA is determined by a sequence of events that includes initiation of transcription by RNA polymerase II, elongation of the trans cr ipt , termina tion of transcription, mRNA capping, polyadenylation, splicing, transport to the cytoplasm, and eventual degradation ...
M H, Meisler, G, Howard
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Glucocorticoids: Effects on Gene Transcription
Proceedings of the American Thoracic Society, 2004Abstract The major antiinflammatory effects of glucocorticoids appear to be due largely to interaction between the activated glucocorticoid receptor and transcription factors, notably nuclear factor-κB (NF-κB) and activator protein-1, that mediate the expression of inflammatory genes. NF-κB switches on inflammatory genes via a process
Ian M, Adcock, Kaz, Ito, Peter J, Barnes
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The Rhesus Gene and the Effect of Consanguinity
Science, 1945It is pointed out that consanguinity among the parents of children affected by erythroblastosis foetalis should be less than in the general population, unless other loci than the R locus are involved in the disease.
C, Stern, D R, Charles
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The Effects of Hallucinogens on Gene Expression
2017The classic serotonergic hallucinogens, or psychedelics, have the ability to profoundly alter perception and behavior. These can include visual distortions, hallucinations, detachment from reality, and mystical experiences. Some psychedelics, like LSD, are able to produce these effects with remarkably low doses of drug.
David A, Martin, Charles D, Nichols
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Changing Genes: Their Effects on Evolution
Bulletin of the Atomic Scientists, 1947There has been much speculation on the possible effects of radiation on human and animal life. The following article describes the functions of genes, the ultimate bearers of heredity, and the influence which their changes may have on the survival of living organisms. Dr. Muller is Professor of Zoology at Indiana University.
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Effects of Emdogain on osteoblast gene expression
Oral Diseases, 2006Objective: Emdogain (EMD) is a protein extract purified from porcine enamel and has been introduced in clinical practice to obtain periodontal regeneration. EMD is composed mainly of amelogenins (90%), while the remaining 10% is composed of non‐amelogenin enamel matrix proteins such as enamelins, tuftelin, amelin and ameloblastin.
Carinci F +8 more
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Tau gene mutations and their effects
Movement Disorders, 2005Tau is the major component of the intracellular filamentous deposits that define a number of neurodegenerative diseases, including the largely sporadic Alzheimer's disease, progressive supranuclear palsy, corticobasal degeneration, Pick's disease, and argyrophilic grain disease, as well as the inherited frontotemporal dementia and parkinsonism linked ...
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Regulation of MAL gene expression in yeast: Gene dosage effects
Molecular and General Genetics MGG, 1987Both the MAL1 and MAL6 loci in Saccharomyces strains have been shown by functional and structural studies to comprise a cluster of at least three genes necessary for maltose utilization. They include regulatory, maltose transport and maltase genes designated MALR, MALT and MALS, respectively.
Goldenthal, M +3 more
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