Results 131 to 140 of about 5,533,099 (347)

Integration of circadian and hypoxia signaling via non‐canonical heterodimerization

FEBS Letters, EarlyView.
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley   +1 more source

RNA-containing extracellular vesicles in infection

RNA Biology
Extracellular vesicles (EVs) are membrane-bound particles released by cells that play vital roles in intercellular communication by transporting diverse biologically active molecules, including RNA molecules, including mRNA, miRNA, lncRNA, and other ...
Kayo Schemiko Almeida, Suélen Andreia Rossi, Lysangela Ronalte Alves   +2 more
doaj   +1 more source

ARH directs megalin to the endocytic recycling compartment to regulate its proteolysis and gene expression [PDF]

, 2013
Mehul Shah, Oscar Y. Baterina, Vanessa Taupin, Marilyn G. Farquhar   +3 more
openalex   +1 more source

The Expression of the StNRAMP2 Gene Determined the Accumulation of Cadmium in Different Tissues of Potato [PDF]

, 2023
Yu-Le Zhang, Tengbing He, Weijun Tian, Yabei Xia, Yeqing He, Minmin Su, Guandi He   +6 more
openalex   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

The effects of the neonicotinoid imidacloprid on gene expression and DNA methylation in the buff-tailed bumblebee Bombus terrestris [PDF]

, 2019
P.S.A. Bebane, Benjamin J. Hunt, Mirko Pegoraro, Alun R. C. Jones, Hollie Marshall, Ezio Rosato, Eamonn B. Mallon   +6 more
openalex   +1 more source

Differential gene expression between callosal and ipsilateral projection neurons in the monkey dorsolateral prefrontal and posterior parietal cortices

, 2022
Dominique Arion, John F. Enwright, Guillermo González‐Burgos, David A. Lewis   +3 more
openalex   +2 more sources

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Discovery of a new predominant cytosine DNA modification that is linked to gene expression in malaria parasites [PDF]

, 2019
Elie Hammam, Guruprasad Ananda, Ameya Sinha, Christine Scheidig‐Benatar, Mylène Bohec, Peter R. Preiser, Peter C. Dedon, Artur Scherf, Shruthi Sridhar Vembar   +8 more
openalex   +1 more source