Results 261 to 270 of about 5,552,491 (299)

Differential gene expression in mouse retina related to regional differences in vulnerability to hyperoxia.

, 2010
Yuan Zhu, Riccardo Natoli, Krisztina Valter, Jonathan Stone   +3 more
openalex   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Clinical Implications of Upregulated <i>RSAD2</i> Gene Expression in Hepatocellular Carcinoma. [PDF]

Diseases
Li L, Tang NLS, Chan SL, Johnson DR, Mo F, Koh J, Kwan TK, Hui EP, Chan LL, Lee KF, Yu SCH, Yeo W.   +11 more
europepmc   +1 more source

Joint imputation and deconvolution of gene expression across spatial transcriptomics platforms. [PDF]

Genome Res
Zheng H, Sarkar H, Raphael BJ.
europepmc   +1 more source

The impact of BCL-2/MYC protein expression and gene abnormality on primary central nervous system diffuse large B-cell lymphoma.

, 2019
Wenjuan Yin, Xianghou Xia, Meijuan Wu, Haiyang Yang, Xiu Zhu, Wenyong Sun, Minghua Ge   +6 more
openalex   +1 more source

The genetic influence of sex on gene expression for blood in pigs. [PDF]

BMC Genomics
Lin Q, Huang J, Zhou T, Chitotombe TT, Teng J, Li J.   +5 more
europepmc   +1 more source

Two-Color Timestamping of Gene Expression with a Chemigenetic Reporter System. [PDF]

Chembiochem
Lämmermann H, Nguyen J, Tamez-Fernández JF, Kuttler F, Bortoli Chapalay J, Chambon M, Turcatti G, Rivera-Fuentes P.   +7 more
europepmc   +1 more source

Regulation of granin neuropeptide gene expression in human brain during development. [PDF]

Front Mol Neurosci
Demsey LL, Podvin S, Hook V.
europepmc   +1 more source