Results 271 to 280 of about 3,053,094 (318)
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Mechanisms of Ageing and Development, 1993
Considerable amount of data has accumulated during the past few years showing several changes in gene expression as a function of age. However, the basic mechanism of aging still remains poorly understood. In this review, we have mainly analysed the data pertaining to the hypothesis that aging is associated with genetic instability and have attempted ...
Tatsuzo Oka +2 more
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Considerable amount of data has accumulated during the past few years showing several changes in gene expression as a function of age. However, the basic mechanism of aging still remains poorly understood. In this review, we have mainly analysed the data pertaining to the hypothesis that aging is associated with genetic instability and have attempted ...
Tatsuzo Oka +2 more
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Annual Review of Genetics, 1970
A hormone is an effector molecule produced in low concentration by one cell which evokes a physiological response in another. In vertebrates, nu merous classes of chemically unrelated compounds such as polypeptides, amino acids, amines, fatty acid derivatives, and steroids have hormonal activity. Certain of these substances probably are themselves the
David W. Martin, Gordon M. Tomkins
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A hormone is an effector molecule produced in low concentration by one cell which evokes a physiological response in another. In vertebrates, nu merous classes of chemically unrelated compounds such as polypeptides, amino acids, amines, fatty acid derivatives, and steroids have hormonal activity. Certain of these substances probably are themselves the
David W. Martin, Gordon M. Tomkins
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Science, 1981
Gene expression in eukaryotes is influenced by a wide variety of mechanisms including the loss, amplification, and rearrangement of genes. Genes are differentially transcribed, and the RNA transcripts are variably utilized. Multigene families regulate the amount, the diversity, and the timing of gene expression.
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Gene expression in eukaryotes is influenced by a wide variety of mechanisms including the loss, amplification, and rearrangement of genes. Genes are differentially transcribed, and the RNA transcripts are variably utilized. Multigene families regulate the amount, the diversity, and the timing of gene expression.
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Philosophical Transactions of the Royal Society of London. B, Biological Sciences, 1981
During the last two decades, zinc has been shown to be a functionally essential component of more than 120 enzymes and concurrently has been recognized as indispensible to normal cellular growth, development and differentiation of all species.
K. H. Falchuk, Bert L. Vallee
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During the last two decades, zinc has been shown to be a functionally essential component of more than 120 enzymes and concurrently has been recognized as indispensible to normal cellular growth, development and differentiation of all species.
K. H. Falchuk, Bert L. Vallee
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On the Expression of a Structural Gene
Journal of Molecular Biology, 1960Experiments were made on the kinetics of β-galactosidase production by zygotes formed upon mating of inducible, lac+(Hfr z+i+), and constitutive, lac−(F−z−i−), strains of Escherichia coli K12. Enzyme formation commenced within two minutes of the time of injection of the z+ gene.
Arthur B. Pardee +3 more
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The expression of immunoglobulin genes
Immunology Today, 1988Abstract Transcription of antibody genes is restricted to lymphoid cells and is a process controlled by multiple DNA elements. However, modulation of expression during B-cell ontogeny is effected by post-transcriptional and post-translational processes.
Graham P. Cook, Michael S. Neuberger
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American Journal of Respiratory Cell and Molecular Biology, 1989
Collagens are extracellular matrix proteins that play important structural roles in many tissues and organs. Thirteen types of collagen, the products of 23 genes, have been described. Most of the collagen genes are developmentally regulated; a given tissue or cell type expresses only a subset of the collagen genes.
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Collagens are extracellular matrix proteins that play important structural roles in many tissues and organs. Thirteen types of collagen, the products of 23 genes, have been described. Most of the collagen genes are developmentally regulated; a given tissue or cell type expresses only a subset of the collagen genes.
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Gene Expression in Atherogenesis
Thrombosis and Haemostasis, 2001SummaryIt is conceivable that the extent and spatio-temperal expression of dozens or even a few hundred genes are significantly altered during the development and progression of atherosclerosis as compared to normal circumstances. Differential gene expression in vascular cells and in blood cells, due to gene-gene and gene-environment interactions can ...
E K Arkenbout +2 more
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Gene Expression in Heterozygotes
Nature, 1962IN many cases a gene appears to function only by synthesizing a polypeptide chain through the mediation of ribonucleic acid (RNA), and hence controlling the synthesis of a protein. A mutation may cause a different polypeptide chain to be synthesized, for example, in the haemoglobinopathies, or may result in failure to produce a polypeptide chain at all.
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1999
Altering the expression of genes has become a rapidly evolving area of research in medicine. The realization that gene expression is important in a wide range of diseases, and not just in inherited disease, has resulted in recognition of the whole fi eld of gene expression as one that may bring new therapeutic options.
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Altering the expression of genes has become a rapidly evolving area of research in medicine. The realization that gene expression is important in a wide range of diseases, and not just in inherited disease, has resulted in recognition of the whole fi eld of gene expression as one that may bring new therapeutic options.
openaire +3 more sources