Results 31 to 40 of about 15,770,266 (354)

Expression quantitative trait loci are highly sensitive to cellular differentiation state [PDF]

open access: yes, 2009
Blood cell development from multipotent hematopoietic stem cells to specialized blood cells is accompanied by drastic changes in gene expression for which the triggers remain mostly unknown.
A Gerrits   +48 more
core   +8 more sources

Different 3' end regions strongly influence the level of gene expression in plant cells [PDF]

open access: yes, 1989
We have investigated the functional role of a 3' end region on the expression of a reporter gene in plant cells. In stably transformed plants, expression of the reporter gene without a plant gene 3' end is variable and depends on the fortuitous presence ...
Ingelbrecht, Ivan   +4 more
core   +1 more source

SpaGCN: Integrating gene expression, spatial location and histology to identify spatial domains and spatially variable genes by graph convolutional network

open access: yesNature Methods, 2021
Recent advances in spatially resolved transcriptomics (SRT) technologies have enabled comprehensive characterization of gene expression patterns in the context of tissue microenvironment. To elucidate spatial gene expression variation, we present SpaGCN,
Jian Hu   +8 more
semanticscholar   +1 more source

Genome‐wide allele‐ and strand‐specific expression profiling

open access: yesMolecular Systems Biology, 2009
Recent reports have shown that most of the genome is transcribed and that transcription frequently occurs concurrently on both DNA strands. In diploid genomes, the expression level of each allele conditions the degree to which sequence polymorphisms ...
Julien Gagneur   +5 more
doaj   +1 more source

Sequencing refractory regions in bird genomes are hotspots for accelerated protein evolution

open access: yesBMC Ecology and Evolution, 2021
Background Approximately 1000 protein encoding genes common for vertebrates are still unannotated in avian genomes. Are these genes evolutionary lost or are they not yet found for technical reasons?
R. Huttener   +11 more
doaj   +1 more source

Localization and Functional Roles of Components of the Translation Apparatus in the Eukaryotic Cell Nucleus

open access: yesCells, 2021
Components of the translation apparatus, including ribosomal proteins, have been found in cell nuclei in various organisms. Components of the translation apparatus are involved in various nuclear processes, particularly those associated with genome ...
Zaur M. Kachaev   +4 more
doaj   +1 more source

Positive selection underlies Faster-Z evolution of gene expression in birds. [PDF]

open access: yes, 2015
The elevated rate of evolution for genes on sex chromosomes compared to autosomes (Fast-X or Fast-Z evolution) can result either from positive selection in the heterogametic sex, or from non-adaptive consequences of reduced relative effective population ...
Dean, R   +4 more
core   +1 more source

The expression of ovomucoid gene* [PDF]

open access: yesBiochemistry and Molecular Biology Education, 2004
AbstractTerms to be familiar with before you start to solve the test: gene expression, isolation of RNA, Northern blotting, hybridization, autoradiography, pre‐mRNA splicing, exons and introns, poly(A) tail, and triplet code.
openaire   +2 more sources

Characterization of RNA in exosomes secreted by human breast cancer cell lines using next-generation sequencing [PDF]

open access: yesPeerJ, 2013
Exosomes are nanosized (30–100 nm) membrane vesicles secreted by most cell types. Exosomes have been found to contain various RNA species including miRNA, mRNA and long non-protein coding RNAs. A number of cancer cells produce elevated levels of exosomes.
Piroon Jenjaroenpun   +5 more
doaj   +2 more sources

Gene Therapy for Acquired and Genetic Cholestasis

open access: yesBiomedicines, 2022
Cholestatic diseases can be caused by the dysfunction of transporters involved in hepatobiliary circulation. Although pharmacological treatments constitute the current standard of care for these diseases, none are curative, with liver transplantation ...
Javier Martínez-García   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy