Results 31 to 40 of about 3,754,670 (317)
Gene Therapy for Acquired and Genetic Cholestasis
Biomedicines, 2022 Cholestatic diseases can be caused by the dysfunction of transporters involved in hepatobiliary circulation. Although pharmacological treatments constitute the current standard of care for these diseases, none are curative, with liver transplantation ...
Javier Martínez-García +4 more
doaj +1 more source
Gene regulatory networks and the role of robustness and stochasticity in the control of gene expression [PDF]
, 2011 In any given cell, thousands of genes are expressed and work in concert to ensure the cell's function, fitness, and survival. Each gene, in turn, must be expressed at the proper time and in the proper amounts to ensure the appropriate functional outcome.
L. T. MacNeil +5 more
core +1 more source
BMC Research Notes, 2022 Objectives The objective of this data set was to identify how interaction between temperature and the sickle-3 (sic-3) mutant alters the global messenger RNA (mRNA) content of Arabidopsis thaliana seedlings.
Carine M. Marshall, Frank G. Harmon
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Rhythmic diel pattern of gene expression in juvenile maize leaf. [PDF]
, 2011 Co-expressed genes belonging to individual clusters are likely to be regulated by common mechanisms. The nocturnal phase of the diurnal cycle involves gross induction of fundamental biochemical processes and should be studied more thoroughly than was ...
Paweł Siedlecki +23 more
core +1 more source
Fuzzy clustering of time series gene expression data with cubic-spline [PDF]
, 2013 Data clustering techniques have been applied to ex- tract information from gene expression data for two decades. A large volume of novel clustering algorithms have been developed and achieved great success.
Ali, Akhtar, Wang, Yu, Angelova, Maia
core +1 more source
BMC Genomics, 2017 Background High-grade serous ovarian carcinoma (HG-SOC) is the dominant tumor histologic type in epithelial ovarian cancers, exhibiting highly aberrant microRNA expression profiles and diverse pathways that collectively determine the disease ...
Vladimir A. Kuznetsov +2 more
doaj +1 more source
Identifying expressed genes [PDF]
Proceedings of the National Academy of Sciences, 2000 The study of expressed genes has had a great impact on biological research (1). Expressed genes are the basic functional units of genomic DNA. Because these regions cannot be identified from genomic sequence information per se, the gene's products, messenger RNAs or proteins, must be isolated from cells, directly sequenced, and identified.
K J, Martin, A B, Pardee
openaire +2 more sources
An extended Kalman filtering approach to modeling nonlinear dynamic gene regulatory networks via short gene expression time series [PDF]
, 2009 Copyright [2009] IEEE. This material is posted here with permission of the IEEE. Such permission of the IEEE does not in any way imply IEEE endorsement of any of Brunel University's products or services.
Liu, Y +4 more
core +1 more source
FGF1 orchestrates circadian hepatic triglyceride secretion
Nature CommunicationsMetabolic dysfunction-Associated Steatotic Liver Disease (MASLD) represents a global health crisis associated with dysregulated hepatic triglyceride (TG) synthesis, oxidation and secretion.
Benan Pelin Sermikli +17 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen +23 more
wiley +1 more source