Results 21 to 30 of about 3,742,529 (317)

Widespread sex differences in gene expression and splicing in the adult human brain. [PDF]

, 2013
There is strong evidence to show that men and women differ in terms of neurodevelopment, neurochemistry and susceptibility to neurodegenerative and neuropsychiatric disease. The molecular basis of these differences remains unclear. Progress in this field
Ramasamy, Adaikalavan, Ryten, Mina, Ramasamy, A, Smith, C, Ryten, M, Trabzuni, D, Walker, R, Smith, Colin, Smith, C; id_orcid, Trabzuni, Daniah, Imran, S, Weale, M, Hardy, John, ?, ?, Weale, Michael E, Hardy, J, North American Brain Expression Consortium, Weale, ME, Imran, Sabaena, Walker, Robert   +19 more
core   +1 more source

Consensus clustering and functional interpretation of gene-expression data [PDF]

, 2004
Microarray analysis using clustering algorithms can suffer from lack of inter-method consistency in assigning related gene-expression profiles to clusters.
Liu, X, Orengo, Christine, Martin, N, Kellam, P., Paul Kellam, Liu, X., Swift, Stephen, Swift, S, Orengo, C.A., Tucker, Allan, Tucker, A., Tucker, A, Liu, XH, Allan Tucker, Vinciotti, Veronica, Christine Orengo, Veronica Vinciotti, Vinciotti, V., Xiaohui Liu, Swift, S., Kellam, P, Liu, Xiaohui, Vinciotti, V, Stephen Swift, Kellam, Paul, Orengo, C, Martin, Nigel, Nigel Martin   +27 more
core   +1 more source

Temporal inhibition of chromatin looping and enhancer accessibility during neuronal remodeling

Nature Communications, 2021
Long-range looping of an enhancer to a promoter (E-P looping) is a key feature of gene activation; thus, regulation of E-P looping could serve as an effective strategy to precisely control gene expression.
Dahong Chen, Catherine E. McManus, Behram Radmanesh, Leah H. Matzat, Elissa P. Lei   +4 more
doaj   +1 more source

Genome‐wide allele‐ and strand‐specific expression profiling

Molecular Systems Biology, 2009
Recent reports have shown that most of the genome is transcribed and that transcription frequently occurs concurrently on both DNA strands. In diploid genomes, the expression level of each allele conditions the degree to which sequence polymorphisms ...
Julien Gagneur, Himanshu Sinha, Fabiana Perocchi, Richard Bourgon, Wolfgang Huber, Lars M Steinmetz   +5 more
doaj   +1 more source

Sequencing refractory regions in bird genomes are hotspots for accelerated protein evolution

BMC Ecology and Evolution, 2021
Background Approximately 1000 protein encoding genes common for vertebrates are still unannotated in avian genomes. Are these genes evolutionary lost or are they not yet found for technical reasons?
R. Huttener, L. Thorrez, T. In’t Veld, M. Granvik, L. Van Lommel, E. Waelkens, R. Derua, K. Lemaire, L. Goyvaerts, S. De Coster, J. Buyse, F. Schuit   +11 more
doaj   +1 more source

Localization and Functional Roles of Components of the Translation Apparatus in the Eukaryotic Cell Nucleus

Cells, 2021
Components of the translation apparatus, including ribosomal proteins, have been found in cell nuclei in various organisms. Components of the translation apparatus are involved in various nuclear processes, particularly those associated with genome ...
Zaur M. Kachaev, Sergey D. Ivashchenko, Eugene N. Kozlov, Lyubov A. Lebedeva, Yulii V. Shidlovskii   +4 more
doaj   +1 more source

The expression of ovomucoid gene* [PDF]

Biochemistry and Molecular Biology Education, 2004
AbstractTerms to be familiar with before you start to solve the test: gene expression, isolation of RNA, Northern blotting, hybridization, autoradiography, pre‐mRNA splicing, exons and introns, poly(A) tail, and triplet code.
openaire   +2 more sources

Characterization of RNA in exosomes secreted by human breast cancer cell lines using next-generation sequencing [PDF]

PeerJ, 2013
Exosomes are nanosized (30–100 nm) membrane vesicles secreted by most cell types. Exosomes have been found to contain various RNA species including miRNA, mRNA and long non-protein coding RNAs. A number of cancer cells produce elevated levels of exosomes.
Piroon Jenjaroenpun, Yuliya Kremenska, Vrundha M. Nair, Maksym Kremenskoy, Baby Joseph, Igor V. Kurochkin   +5 more
doaj   +2 more sources

Gene Therapy for Acquired and Genetic Cholestasis

Biomedicines, 2022
Cholestatic diseases can be caused by the dysfunction of transporters involved in hepatobiliary circulation. Although pharmacological treatments constitute the current standard of care for these diseases, none are curative, with liver transplantation ...
Javier Martínez-García, Angie Molina, Gloria González-Aseguinolaza, Nicholas D. Weber, Cristian Smerdou   +4 more
doaj   +1 more source

Impact of the sickle mutant and temperature on the structure of transcripts and RNAs from Arabidopsis thaliana

BMC Research Notes, 2022
Objectives The objective of this data set was to identify how interaction between temperature and the sickle-3 (sic-3) mutant alters the global messenger RNA (mRNA) content of Arabidopsis thaliana seedlings.
Carine M. Marshall, Frank G. Harmon
doaj   +1 more source