Results 61 to 70 of about 3,887,902 (293)
Motor Nucleus of the Trigeminal Nerve [PDF]
This report contains a summary of expression patterns for genes that are enriched in the motor nucleus of the trigeminal nerve (V) of the pons. All data is derived from the Allen Brain Atlas (ABA) in situ hybridization mouse project. The structure's
Allen Institute for Brain Science +3 more
core +2 more sources
Gene Expression Data Clustering
Gene expression analysis is becoming very important in order to understand complex living organisms. Rather than analyzing genes individually, there is more powerful approach, microarray technology to analyze the genes expression in high throughput. This new approach brings new analyses problems that make the interpretation difficult. To understand the
openaire +2 more sources
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács +8 more
wiley +1 more source
Background Although, systematic analysis of gene annotation is a powerful tool for interpreting gene expression data, it sometimes is blurred by incomplete gene annotation, missing expression response of key genes and secondary gene expression responses.
Nielsen Henrik B, Manijak Mieszko P
doaj +1 more source
Extreme self-organization in networks constructed from gene expression data [PDF]
We study networks constructed from gene expression data obtained from many types of cancers. The networks are constructed by connecting vertices that belong to each others' list of K-nearest-neighbors, with K being an a priori selected non-negative ...
D. Gerhold +4 more
core +1 more source
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson +3 more
wiley +1 more source
A microfluidic processor for gene expression profiling of single human embryonic stem cells [PDF]
The gene expression of human embryonic stem cells (hESC) is a critical aspect for understanding the normal and pathological development of human cells and tissues.
Chen, Yan +6 more
core +1 more source
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski +9 more
wiley +1 more source
A linear mixed model approach to gene expression-tumor aneuploidy association studies. [PDF]
Aneuploidy, defined as abnormal chromosome number or somatic DNA copy number, is a characteristic of many aggressive tumors and is thought to drive tumorigenesis.
Balanis, Nikolas G +3 more
core
Gene-Ontology-based clustering of gene expression data [PDF]
Abstract Summary: The expected correlation between genetic co-regulation and affiliation to a common biological process is not necessarily the case when numerical cluster algorithms are applied to gene expression data. GO-Cluster uses the tree structure of the Gene Ontology database as a framework for numerical clustering, and thus ...
Adryan, B., Schuh, R.
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