Results 41 to 50 of about 12,165,430 (302)

Expressive genomic hybridisation: gene expression profiling at the cytogenetic level [PDF]

Molecular Pathology, 2003
To describe a cytogenetic technique suitable for the rapid assessment of global gene expression that is based on comparative genomic hybridisation (CGH), and to use it to understand the relation between genetic amplifications and gene expression.Whereas traditional CGH uses DNA as test and reference in hybridisations, expressive genomic hybridisation ...
F, Al-Mulla, M, Al-Maghrebi, G, Varadharaj   +2 more
openaire   +2 more sources

Gene expression levels of inflammatory mediators in diabetic foot ulcer patients

مجلة مركز بحوث التقنيات الاحيائية, 2023
 Background: Diabetic foot ulcer (DFU) is a common serious complication of diabetes. Nowadays there is a suggestion that referred to the fact the chronicity of DFU is a result of the positive feedback of proinflammatory cytokines production ...
Israa K. Hussein, Wafaa S. Shani
doaj   +1 more source

Mitochondrial impairment increases FL-PINK1 levels by calcium-dependent gene expression

Neurobiology of Disease, 2014
Mutations of the PTEN-induced kinase 1 (PINK1) gene are a cause of autosomal recessive Parkinson's disease (PD). This gene encodes a mitochondrial serine/threonine kinase, which is partly localized to mitochondria, and has been shown to play a role in ...
Rubén Gómez-Sánchez, Matthew E. Gegg, José M. Bravo-San Pedro, Mireia Niso-Santano, Lydia Alvarez-Erviti, Elisa Pizarro-Estrella, Yolanda Gutiérrez-Martín, Alberto Alvarez-Barrientos, José M. Fuentes, Rosa Ana González-Polo, Anthony H.V. Schapira   +10 more
doaj   +1 more source

A Brassica exon array for whole-transcript gene expression profiling [PDF]

, 2010
Affymetrix GeneChip® arrays are used widely to study transcriptional changes in response to developmental and environmental stimuli. GeneChip® arrays comprise multiple 25-mer oligonucleotide probes per gene and retain certain advantages over direct ...
King Graham J., Broadley, MR, May Sean T., John P. Hammond, Bowen, H. C., Bowen, HC, Hammond, J. P., Lochlainn, Seosamh O., Neil S Graham, Philip J White, Graham J. King, Broadley, Martin R., Ó Lochlainn Seosamh, May, ST, Hammond, John P., Graham, NS, Love Christopher G., Christopher G Love, Helen C. Bowen, Graham, N. S., Sean T. May, Philip J. White, Christopher G. Love, Graham, Neil S., O Lochlainn, S., Hammond John P., White, PJ, Graham J King, Ó Lochlainn, Seosamh, May, S. T., Hammond, JP, Love, Christopher G., Love, CG, Helen C Bowen, John P Hammond, Seosamh O Lochlainn, King, GJ, King, G. J., King, Graham J., Broadley, M. R., Broadley Martin R., May, Sean T., Bowen Helen C., Martin R. Broadley, Sean T May, Martin R Broadley, White, P. J., King , Graham J., Love, C. G., Neil S. Graham, White Philip J., White, Philip J., Graham Neil S., Lochlainn, SO, Bowen, Helen C.   +54 more
core   +1 more source

Functional and Mechanistic Insights into the Fatty-Acid CoA Ligase FadK in Escherichia coli

Frontiers in Bioscience-Landmark
Background: Escherichia coli (E. coli) is a common opportunistic bacterial pathogen in both human and animal populations. Fatty acids serve as the central carbon and energy source, a process mediated by fatty acid-coenzyme A (CoA ...
Dafeng Liu, Ablikim Abdiriyim, Lvxia Zhang, Feng Yu   +3 more
doaj   +1 more source

Nonlinear Dynamics in Gene Regulation Promote Robustness and Evolvability of Gene Expression Levels.

PLoS ONE, 2016
Cellular phenotypes underpinned by regulatory networks need to respond to evolutionary pressures to allow adaptation, but at the same time be robust to perturbations.
Arno Steinacher, Declan G Bates, Ozgur E Akman, Orkun S Soyer   +3 more
doaj   +1 more source

Autism and increased paternal age related changes in global levels of gene expression regulation. [PDF]

PLoS ONE, 2011
A causal role of mutations in multiple general transcription factors in neurodevelopmental disorders including autism suggested that alterations in global levels of gene expression regulation might also relate to disease risk in sporadic cases of autism.
Mark D Alter, Rutwik Kharkar, Keri E Ramsey, David W Craig, Raun D Melmed, Theresa A Grebe, R Curtis Bay, Sharman Ober-Reynolds, Janet Kirwan, Josh J Jones, J Blake Turner, Rene Hen, Dietrich A Stephan   +12 more
doaj   +1 more source

Decision Trees for the Analysis of Gene Expression Levels of COVID-19: An Association with Alzheimer’s Disease

BioMedInformatics
COVID-19 has caused millions of deaths around the world. The respiratory system is the main target of this disease, but it has also been reported to attack the central nervous system, creating a neuroinflammatory environment with the release of ...
Jesús Alberto Torres-Sosa, Gonzalo Emiliano Aranda-Abreu, Nicandro Cruz-Ramírez, Sonia Lilia Mestizo-Gutiérrez   +3 more
doaj   +1 more source

Gene Expression and Methylation Levels of PCSK9 Gene in Iraqi Patients with Coronary Artery Disease

مجلة بغداد للعلوم, 2023
The expression of the Proprotein Convertase Subtilisin/Kexin Type 9 gene (PCSK9) is inextricably related to lipid levels and a risk of atherosclerotic coronary artery disease (ASCAD).
Marwa M. Al-Attar, Salwa J. Al-Awadi Al-Awadi, Shaimaa Y. Abdulfattah   +2 more
doaj   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source