Results 21 to 30 of about 12,165,430 (302)

Tumor-stroma derived gene expression patterns as prognosticators in breast cancer [PDF]

, 2010
The stroma, which embeds epithelial cells, plays a major role in the shaping and physiological regulation of animal organs such as the breast. Aberrant functioning of the stroma was found to support tumorigenesis and cancer progression.
Rajski, Michal
core   +1 more source

Association of the CCR5 gene with juvenile idiopathic arthritis [PDF]

, 2010
The CC chemokine receptor 5 (CCR5) has been shown to be important in the recruitment of T-helper cells to the synovium, where they accumulate, drive the inflammatory process and the consequent synovitis and joint destruction.
Martin, P., BSPAR Study Group, Barton, A., UKRAG Consortium, Worthington, J., Gardner-Medwin, J. [CAPS and BSPAR Study Groups], Thomson, W., W Thomson, Flynn, E., A Hinks, E Flynn, J Packham, Packham, J., Hinks, A., S Eyre, J Worthington, Eyre, S.; id_orcid, Eyre, S., Barton, A.; id_orcid, P Martin, Childhood Arthritis Prospective Study (CAPS), Martin, P.; id_orcid, A Barton   +22 more
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Divergent patterns of selection on metabolite levels and gene expression

BMC Ecology and Evolution, 2021
Background Natural selection can act on multiple genes in the same pathway, leading to polygenic adaptation. For example, adaptive changes were found to down-regulate six genes involved in ergosterol biosynthesis—an essential pathway targeted by many ...
Alexander F. Kern, Grace Xiaolu Yang, Neil M. Khosla, Roy Moh Lik Ang, Michael P. Snyder, Hunter B. Fraser   +5 more
doaj   +1 more source

Gene expression levels in lymphoma [PDF]

Blood, 2007
[Comment on Sakhinia et al, page 3922][1]In the United States, 59 000 people were diagnosed with non-Hodgkin lymphoma during 2006, and 19 000 died of the disease. Translational molecular research is a high priority; however, routine measurement of predictive gene expression levels has ...
openaire   +1 more source

Correlated levels of mRNA and soma size in single identified neurons: evidence for compartment-specific regulation of gene expression

Frontiers in Molecular Neuroscience, 2010
In addition to the overall complexity of transcriptional regulation, cells also must take into account the subcellular distribution of these gene products. This is particularly challenging for morphologically complex cells such as neurons.
Joseph L Ransdell, Tyler B Faust, David J Schulz   +2 more
doaj   +1 more source

An extended Kalman filtering approach to modeling nonlinear dynamic gene regulatory networks via short gene expression time series [PDF]

, 2009
Copyright [2009] IEEE. This material is posted here with permission of the IEEE. Such permission of the IEEE does not in any way imply IEEE endorsement of any of Brunel University's products or services.
Liu, Y, Liu, X, Wang, Z, Liang, Y, Vinciotti, V   +4 more
core   +1 more source

Gene model-related m6A expression levels predict the risk of preeclampsia

BMC Medical Genomics, 2022
Background This is the first study to explore the potential functions and expression patterns of RNA N6-methyladenosine (m6A) and potential related genes in preeclampsia.
Yiwei Li, Can Chen, Mengyuan Diao, Yanli Wei, Ying Zhu, Wei Hu   +5 more
doaj   +1 more source

Gene Expression Modifications by Temperature-Toxicants Interactions in Caenorhabditis elegans [PDF]

, 2011
Although organophosphorus pesticides (OP) share a common mode of action, there is increased awareness that they elicit a diverse range of gene expression responses.
Vinuela Rodriguez, A., Kammenga Jan E., Joost A. G. Riksen, Riksen Joost A. G., Ana Viñuela, L Basten Snoek, Viñuela Ana, Jan E. Kammenga, Joost A G Riksen, Kammenga, J.E., Snoek, L.B., L. Basten Snoek, Jan E Kammenga, Snoek L. Basten, Riksen, J.A.G.   +14 more
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Structural and functional characterization of CSDA protein complexes involved in the modulation of fetal globin gene expression [PDF]

, 2009
Impaired switching from fetal hemoglobin (HbF) to adult globin gene expression leads to hereditary persistence of fetal hemoglobin (HPFH) in adult life.
Gaudino, Sara
core   +1 more source

Low Oxygen Levels Induce Early Luteinization Associated Changes in Bovine Granulosa Cells

Frontiers in Physiology, 2018
During follicle maturation, oxygen levels continuously decrease in the follicular fluid and reach lowest levels in the preovulatory follicle. The current study was designed to comprehensively understand effects of low oxygen levels on bovine granulosa ...
Vijay S. Baddela, Arpna Sharma, Torsten Viergutz, Dirk Koczan, Jens Vanselow   +4 more
doaj   +1 more source