Results 1 to 10 of about 12,165,430 (302)
Multivariate Surprisal Analysis of Gene Expression Levels [PDF]
Entropy, 2016 We consider here multivariate data which we understand as the problem where each data point i is measured for two or more distinct variables. In a typical situation there are many data points i while the range of the different variables is more limited ...
Francoise Remacle +2 more
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The genetic architecture of gene expression levels in wild baboons
eLife, 2015 Primate evolution has been argued to result, in part, from changes in how genes are regulated. However, we still know little about gene regulation in natural primate populations.
Jenny Tung +4 more
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The evolution of gene expression levels in mammalian organs
Nature, 2011 Changes in gene expression are thought to underlie many of the phenotypic differences between species. However, large-scale analyses of gene expression evolution were until recently prevented by technological limitations. Here we report the sequencing of polyadenylated RNA from six organs across ten species that represent all major mammalian lineages ...
Gabor Csárdi +2 more
exaly +6 more sources
Agronomy, 2022 The composition and content of sugar and acid are important indicators of organ development and the quality of horticultural products. B. juncea is an important vegetable in the cruciferous family, with a swollen fleshy stem as the edible organ ...
Fangjie Xie +7 more
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A gene-level test for directional selection on gene expression
GENETICS, 2022 Abstract Most variants identified in human genome-wide association studies and scans for selection are noncoding. Interpretation of their effects and the way in which they contribute to phenotypic variation and adaptation in human populations is therefore limited by our understanding of gene regulation and the difficulty of ...
Laura L. Colbran +2 more
openaire +2 more sources
Histone modification levels are predictive for gene expression [PDF]
Proceedings of the National Academy of Sciences, 2010 Histones are frequently decorated with covalent modifications. These histone modifications are thought to be involved in various chromatin-dependent processes including transcription. To elucidate the relationship between histone modifications and transcription, we derived quantitative models to predict the expression level of genes from histone ...
Karlic, R. +4 more
openaire +3 more sources
MiREx: mRNA levels prediction from gene sequence and miRNA target knowledge
BMC Bioinformatics, 2023 Messenger RNA (mRNA) has an essential role in the protein production process. Predicting mRNA expression levels accurately is crucial for understanding gene regulation, and various models (statistical and neural network-based) have been developed for ...
Elena Pianfetti +3 more
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Floral pathway integrator gene expression mediates gradual transmission of environmental and endogenous cues to flowering time [PDF]
PeerJ, 2017 The appropriate timing of flowering is crucial for the reproductive success of plants. Hence, intricate genetic networks integrate various environmental and endogenous cues such as temperature or hormonal statues.
Aalt D.J. van Dijk, Jaap Molenaar
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Protocol for Titrating Gene Expression Levels in Budding Yeast
STAR Protocols, 2020 Summary: The biological phenotype is affected by the level of gene expression. Here, we provide a step-by-step protocol for precisely titrating and quantitatively observing the target gene expression level in budding yeast by manipulating its copy number
Yimiao Qu +3 more
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Variation in the large-scale organization of gene expression levels in the hippocampus relates to stable epigenetic variability in behavior. [PDF]
PLoS ONE, 2008 Despite sharing the same genes, identical twins demonstrate substantial variability in behavioral traits and in their risk for disease. Epigenetic factors-DNA and chromatin modifications that affect levels of gene expression without affecting the DNA ...
Mark D Alter +6 more
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