Results 1 to 10 of about 2,900,843 (394)

Gene Expression Commons: an open platform for absolute gene expression profiling. [PDF]

PLoS ONE, 2012
Gene expression profiling using microarrays has been limited to comparisons of gene expression between small numbers of samples within individual experiments.
Jun Seita, Debashis Sahoo, Derrick J Rossi, Deepta Bhattacharya, Thomas Serwold, Matthew A Inlay, Lauren I R Ehrlich, John W Fathman, David L Dill, Irving L Weissman   +9 more
doaj   +6 more sources

Circulating MicroRNAs in the Second Trimester From Pregnant Women Who Subsequently Developed Preeclampsia: Potential Candidates as Predictive Biomarkers and Pathway Analysis for Target Genes of miR-204-5p

Frontiers in Physiology, 2021
MicroRNAs (miRNAs) play an important role in the pathophysiology of preeclampsia (PE). However, the expression of circulating miRNAs was not analyzed in the second trimester of pregnancy, a period of major relevance to identify predictive biomarkers for ...
Marcelo R. Luizon, Izabela M. C. A. Conceição, Sarah Viana-Mattioli, Mayara Caldeira-Dias, Ricardo C. Cavalli, Valeria C. Sandrim   +5 more
doaj   +1 more source

Gene expression profiling

European Journal of Cancer Supplements, 2008
Gene expression profiling measures the relative abundance of a large number of individual mRNA species within the context of a total mRNA population that has been isolated and purified from a target biological sample. The technology for achieving this evolved from low-Throughput membrane-based probeto- target hybridization assays (northern and Southern
C. Sotiriou, P. Dinh
  +5 more sources

3'-end sequencing for expression quantification (3SEQ) from archival tumor samples. [PDF]

PLoS ONE, 2010
Gene expression microarrays are the most widely used technique for genome-wide expression profiling. However, microarrays do not perform well on formalin fixed paraffin embedded tissue (FFPET).
Andrew H Beck, Ziming Weng, Daniela M Witten, Shirley Zhu, Joseph W Foley, Phil Lacroute, Cheryl L Smith, Robert Tibshirani, Matt van de Rijn, Arend Sidow, Robert B West   +10 more
doaj   +1 more source

Pathway-targeting gene matrix for Drosophila gene set enrichment analysis.

PLoS ONE, 2021
Gene Set Enrichment Analysis (GSEA) is a powerful algorithm to determine biased pathways between groups based on expression profiling. However, for fruit fly, a popular animal model, gene matrixes for GSEA are unavailable. This study provides the pathway-
Jack Cheng, Lee-Fen Hsu, Ying-Hsu Juan, Hsin-Ping Liu, Wei-Yong Lin   +4 more
doaj   +2 more sources

Global assessment of organ specific basal gene expression over a diurnal cycle with analyses of gene copies exhibiting cyclic expression patterns

BMC Genomics, 2020
Background Studying functional divergences between paralogs that originated from genome duplication is a significant topic in investigating molecular evolution.
Yuan Lu, Mikki Boswell, William Boswell, Raquel Ybanez Salinas, Markita Savage, Jose Reyes, Sean Walter, Rebecca Marks, Trevor Gonzalez, Geraldo Medrano, Wesley C. Warren, Manfred Schartl, Ronald B. Walter   +12 more
doaj   +1 more source

Comparison between Oncotype DX test and standard prognostic criteria in estrogen receptor positive early-stage breast cancer [PDF]

Einstein (São Paulo), 2011
Objective: To compare the prognosis estimated by standardprognostic criteria versus the prognosis estimated by the OncotypeDX. Methods: A retrospective study was performed on 22 patientswith positive estrogen receptor, early-stage breast cancer whohad an
Marcelo Roberto Pereira Freitas, Sergio Daniel Simon   +1 more
doaj   +4 more sources

Transformation of Mature Osteoblasts into Bone Lining Cells and RNA Sequencing-Based Transcriptome Profiling of Mouse Bone during Mechanical Unloading [PDF]

Endocrinology and Metabolism, 2020
Background We investigated RNA sequencing-based transcriptome profiling and the transformation of mature osteoblasts into bone lining cells (BLCs) through a lineage tracing study to better understand the effect of mechanical unloading on bone loss ...
A Ram Hong, Kwangsoo Kim, Ji Yeon Lee, Jae-Yeon Yang, Jung Hee Kim, Chan Soo Shin, Sang Wan Kim   +6 more
doaj   +1 more source

Cancer gene prioritization by integrative analysis of mRNA expression and DNA copy number data: a comparative review [PDF]

, 2011
A variety of genome-wide profiling techniques are available to probe complementary aspects of genome structure and function. Integrative analysis of heterogeneous data sources can reveal higher-level interactions that cannot be detected based on ...
Akavia, Andrews, Baasiri, Chin, Dai, De Bie, Futreal, H.-U. Klein, Haverty, Hawkins, Hyman, Johnson, Kao, L. Lahti, M. Dugas, M. Schafer, McLendon, Menezes, Mullighan, Mullighan, Myllykangas, Olshen, Ortiz-Estevez, Phillips, Qin, S. Bicciato, Solvang, Soneson, Stranger, van Wieringen, van Wieringen   +30 more
core   +2 more sources

Bacterial riboproteogenomics : the era of N-terminal proteoform existence revealed [PDF]

, 2020
With the rapid increase in the number of sequenced prokaryotic genomes, relying on automated gene annotation became a necessity. Multiple lines of evidence, however, suggest that current bacterial genome annotations may contain inconsistencies and are ...
Fijalkowska, Daria, Fijalkowski, Igor, Van Damme, Petra, Willems, Patrick   +3 more
core   +2 more sources