Results 1 to 10 of about 466,846 (213)

Gene expression profiling reveals enhanced nutrient and drug metabolism and maturation of hiPSC-derived intestine-on-chip relative to organoids and Transwells. [PDF]

Stem Cell Reports
Moerkens R, Mooiweer J, Smits E, Berg M, Ramírez-Sánchez AD, Modderman R, Puschhof J, Pleguezuelos-Manzano C, Barrett RJ, Wijmenga C, Jonkers IH, Withoff S.   +11 more
europepmc   +2 more sources

Circulating MicroRNAs in the Second Trimester From Pregnant Women Who Subsequently Developed Preeclampsia: Potential Candidates as Predictive Biomarkers and Pathway Analysis for Target Genes of miR-204-5p

Frontiers in Physiology, 2021
MicroRNAs (miRNAs) play an important role in the pathophysiology of preeclampsia (PE). However, the expression of circulating miRNAs was not analyzed in the second trimester of pregnancy, a period of major relevance to identify predictive biomarkers for ...
Marcelo R. Luizon, Izabela M. C. A. Conceição, Sarah Viana-Mattioli, Mayara Caldeira-Dias, Ricardo C. Cavalli, Valeria C. Sandrim   +5 more
doaj   +1 more source

Gene expression profiling

European Journal of Cancer Supplements, 2008
Gene expression profiling measures the relative abundance of a large number of individual mRNA species within the context of a total mRNA population that has been isolated and purified from a target biological sample. The technology for achieving this evolved from low-Throughput membrane-based probeto- target hybridization assays (northern and Southern
C. Sotiriou, P. Dinh
  +5 more sources

3'-end sequencing for expression quantification (3SEQ) from archival tumor samples. [PDF]

PLoS ONE, 2010
Gene expression microarrays are the most widely used technique for genome-wide expression profiling. However, microarrays do not perform well on formalin fixed paraffin embedded tissue (FFPET).
Andrew H Beck, Ziming Weng, Daniela M Witten, Shirley Zhu, Joseph W Foley, Phil Lacroute, Cheryl L Smith, Robert Tibshirani, Matt van de Rijn, Arend Sidow, Robert B West   +10 more
doaj   +1 more source

Pathway-targeting gene matrix for Drosophila gene set enrichment analysis

PLoS ONE, 2021
Gene Set Enrichment Analysis (GSEA) is a powerful algorithm to determine biased pathways between groups based on expression profiling. However, for fruit fly, a popular animal model, gene matrixes for GSEA are unavailable. This study provides the pathway-
Jack Cheng, Lee-Fen Hsu, Ying-Hsu Juan, Hsin-Ping Liu, Wei-Yong Lin   +4 more
doaj   +2 more sources

Gene Expression Commons: an open platform for absolute gene expression profiling. [PDF]

PLoS ONE, 2012
Gene expression profiling using microarrays has been limited to comparisons of gene expression between small numbers of samples within individual experiments.
Jun Seita, Debashis Sahoo, Derrick J Rossi, Deepta Bhattacharya, Thomas Serwold, Matthew A Inlay, Lauren I R Ehrlich, John W Fathman, David L Dill, Irving L Weissman   +9 more
doaj   +1 more source

Global assessment of organ specific basal gene expression over a diurnal cycle with analyses of gene copies exhibiting cyclic expression patterns

BMC Genomics, 2020
Background Studying functional divergences between paralogs that originated from genome duplication is a significant topic in investigating molecular evolution.
Yuan Lu, Mikki Boswell, William Boswell, Raquel Ybanez Salinas, Markita Savage, Jose Reyes, Sean Walter, Rebecca Marks, Trevor Gonzalez, Geraldo Medrano, Wesley C. Warren, Manfred Schartl, Ronald B. Walter   +12 more
doaj   +1 more source

Comparison between Oncotype DX test and standard prognostic criteria in estrogen receptor positive early-stage breast cancer [PDF]

Einstein (São Paulo), 2011
Objective: To compare the prognosis estimated by standardprognostic criteria versus the prognosis estimated by the OncotypeDX. Methods: A retrospective study was performed on 22 patientswith positive estrogen receptor, early-stage breast cancer whohad an
Marcelo Roberto Pereira Freitas, Sergio Daniel Simon   +1 more
doaj   +4 more sources

Transformation of Mature Osteoblasts into Bone Lining Cells and RNA Sequencing-Based Transcriptome Profiling of Mouse Bone during Mechanical Unloading [PDF]

Endocrinology and Metabolism, 2020
Background We investigated RNA sequencing-based transcriptome profiling and the transformation of mature osteoblasts into bone lining cells (BLCs) through a lineage tracing study to better understand the effect of mechanical unloading on bone loss ...
A Ram Hong, Kwangsoo Kim, Ji Yeon Lee, Jae-Yeon Yang, Jung Hee Kim, Chan Soo Shin, Sang Wan Kim   +6 more
doaj   +1 more source

Exon and junction microarrays detect widespread mouse strain- and sex-bias expression differences

BMC Genomics, 2008
Background Studies have shown that genetic and sex differences strongly influence gene expression in mice. Given the diversity and complexity of transcripts produced by alternative splicing, we sought to use microarrays to establish the extent of ...
Schadt Eric E, Russell Archie, Kulkarni Amit V, Shah Jyoti K, Edwards Stephen, GuhaThakurta Debraj, Modrek Barmak, Su Wan-Lin, Johnson Jason M, Castle John C   +9 more
doaj   +1 more source