Results 11 to 20 of about 4,727,278 (305)

A Brassica exon array for whole-transcript gene expression profiling [PDF]

open access: yes, 2010
Affymetrix GeneChip® arrays are used widely to study transcriptional changes in response to developmental and environmental stimuli. GeneChip® arrays comprise multiple 25-mer oligonucleotide probes per gene and retain certain advantages over direct ...
King Graham J.   +54 more
core   +1 more source

Exon and junction microarrays detect widespread mouse strain- and sex-bias expression differences

open access: yesBMC Genomics, 2008
Background Studies have shown that genetic and sex differences strongly influence gene expression in mice. Given the diversity and complexity of transcripts produced by alternative splicing, we sought to use microarrays to establish the extent of ...
Schadt Eric E   +9 more
doaj   +1 more source

Perceiving molecular evolution processes in Escherichia coli by comprehensive metabolite and gene expression profiling [PDF]

open access: yes, 2008
Vijayendran C, Barsch A, Friehs K, Niehaus K, Becker A, Flaschel E. Perceiving molecular evolution processes in Escherichia coli by comprehensive metabolite and gene expression profiling. GENOME BIOLOGY.
Flaschel, Erwin   +5 more
core   +1 more source

Gene expression analysis in microdissected renal tissue - Current challenges and strategies [PDF]

open access: yes, 2002
The architecture and compartmentalization of the kidney has stimulated the development of an array of microtechniques to study the functional differences between the distinct nephron segments. With the vast amounts of genomic sequence data now available,
Cohen, C. D., Kretzler, M.
core   +1 more source

Profound effect of profiling platform and normalization strategy on detection of differentially expressed microRNAs [PDF]

open access: yes, 2012
Adequate normalization minimizes the effects of systematic technical variations and is a prerequisite for getting meaningful biological changes. However, there is inconsistency about miRNA normalization performances and recommendations.
Wagner, Carola   +4 more
core   +1 more source

Use of homologous and heterologous gene expression profiling tools to characterize transcription dynamics during apple fruit maturation and ripening [PDF]

open access: yes, 2010
Background Fruit development, maturation and ripening consists of a complex series of biochemical and physiological changes that in climacteric fruits, including apple and tomato, are coordinated by the gaseous hormone ethylene.
Valeria Soglio   +56 more
core   +1 more source

Gene Expression Profiling

open access: yesEuropean Journal of Cancer Supplements, 2008
Gene expression profiling measures the relative abundance of a large number of individual mRNA species within the context of a total mRNA population that has been isolated and purified from a target biological sample. The technology for achieving this evolved from low-Throughput membrane-based probeto- target hybridization assays (northern and Southern
C. Sotiriou, P. Dinh
  +5 more sources

Gene expression profiling en association with prion-related lesions in the medulla oblongata of symptomatic natural scrapie animals. [PDF]

open access: yes, 2011
The pathogenesis of natural scrapie and other prion diseases remains unclear. Examining transcriptome variations in infected versus control animals may highlight new genes potentially involved in some of the molecular mechanisms of prion-induced ...
Bossers, A.   +34 more
core   +2 more sources

High-throughput SuperSAGE for digital gene expression analysis of multiple samples using next generation sequencing [PDF]

open access: yes, 2010
We established a protocol of the SuperSAGE technology combined with next-generation sequencing, coined "High- Throughput (HT-) SuperSAGE". SuperSAGE is a method of digital gene expression profiling that allows isolation of 26-bp tag fragments from ...
Schroth, G.P.   +68 more
core   +1 more source

Gene Expression Profiling of Xeroderma Pigmentosum

open access: yesHereditary Cancer in Clinical Practice, 2006
Xeroderma pigmentosum (XP) is a rare recessive disorder that is characterized by extreme sensitivity to UV light. UV light exposure results in the formation of DNA damage such as cyclobutane dimers and (6-4) photoproducts. Nucleotide excision repair (NER)
Bowden Nikola A   +2 more
doaj   +1 more source

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